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Synchronized latency reversal and immune clearance by a multifunctional fusion protein enables HIV-1 reservoir reduction

Latent HIV reservoirs evade both antiviral therapy and immune surveillance. Luo and colleagues develop a multifunctional fusion protein that couples reservoir reactivation with targeted immune engagement and clearance, offering a coordinated strategy to expose and eliminate persistent HIV-infected cells.
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Can AI Agents Detect and Repair Artifact Drift in Network Experiments?

arXiv:2609.09849v1 Announce Type: cross Abstract: In recent years, AI agents have evolved into capable assistants that carry out multi-step tasks in digital environments. The network systems community is beginning to explore these capabilities in operational and experimental settings. However, an agent operating in network systems should not be judged solely by whether it completes the immediate task. The experiment record it modifies must also remain trustworthy. We call this property artifact integrity: the record's claims must remain supported by the available evidence, confined to the scope established by that evidence, and traceable through the artifacts that encode their support. To make this property measurable, we introduce NetArtifactBench, which tests whether AI agents can repair inconsistent records derived from public network-system artifacts while preserving claims that remain supported. The benchmark contains 52 instances with injected inconsistencies ranging from direct contradictions to unstated relations spread across several artifacts. We evaluate 23 agent configurations across three general-purpose AI agent runtimes using deterministic scoring. The average contract pass rate is 65.3 % across 5,980 outputs, but no agent runtime exceeds 30 % when repair requires recovering implicit relations and propagating changes across artifacts. These results reveal a sharp boundary between local correction and complete record-level repair. Therefore, we argue that artifact integrity should become a first-class design and evaluation requirement for AI agents operating on network systems.
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Bit-Flip Attacks on Vision-Language-Action Models: Action-Decoding Architecture Shapes the Vulnerability

arXiv:2608.15475v3 Announce Type: replace-cross Abstract: Quantized Vision-Language-Action (VLA) models expose a weight-fault surface: Rowhammer-style faults can corrupt deployed INT8 bits. We present the first bit-flip attack on a VLA: a few gradient-selected flips reduce closed-loop success to $0\%$, while hundreds of random flips are harmless. Across four model variants spanning three action-head families, damaging bits concentrate in a few action-generating layers, but the empirical budget depends sharply on the head: direct regression and token policies fall in $1$--$5$ flips, whereas the evaluated flow-matching policies require ${\sim}100$--$300$. Our fixed-direction manifold-escape loss cuts \pizero{}'s budget from ${\sim}1000$ to ${\sim}100$ flips, and a matched five-direction sweep shows that the attack is not specific to an all-positive direction. On a direct head, protecting $3.1\%$ of weights preserves $60\%$ success at $K{=}100$, and protecting $5.3\%$ moves the open-loop break threshold from 3 to 100 flips. Finally, task-calibrated emulated $K{=}100$ flips yield $0/20$ real-robot successes, versus $14/20$ clean and $16/20$ global-random. Weight integrity is therefore a security boundary for embodied foundation models. Code is included as ancillary material.
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