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Commensal <i>Nakaseomyces glabratus</i> migrates into prostate tumors to accelerate cancer progression

✇Nature Cancer
By: Ping Lai · Lei Liu · Nicolò Pernigoni · Yingxi Du · Daniele Braga · Martina Troiani · Giuseppe Attanasio · Yuxin Li · Pan Song · Emiliano Pasquini · Tanja Rezzonico Jost · Xiaowen Huang · Martino Maddalena · Simone Mosole · Andrea Rinaldi · Giovanna Pecoraro · Martino Pedrani · Aurora Valdata · Nicolò Bancaro · Luisa Maraccani · Alessandra De Giani · Wei Yuan · Lewis Gallagher · Khobe Chandran · Penny Flohr · Pasquale Rescigno · Giuseppe Reitano · Alessandro Morlacco · Fabrizio Dal Moro · Isabella Giacomini · Monica Montopoli · Matteo Brunelli · Serena Pedron · Ricardo Pereira Mestre · Raad Z. Gharaibeh · Christian Jobin · Silke Gillessen Sommer · Johann de Bono · Andrea Alimonti

Nature Cancer, Published online: 09 September 2026; doi:10.1038/s43018-026-01229-9

Lai et al. show that Nakaseomyces glabratus is enriched in fecal and tumor samples of patients with castration-resistant prostate cancer and that administration of the fungus accelerates cancer progression in prostate cancer-bearing castrated mice.
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Lipotoxicity-induced ER-mitochondrial hypercoupling activates the mtDNA-cGAS-STING-NF-κB axis to drive follicular arrest in metabolically compromised PCOS

✇Cell Death Discovery nature.com science feeds
By: Mingrui Xue · Qi Zhu · Shuli Zhang · Guangzong Zhao · Xiaoqi Hong · Di Pang · Yue Xu · Xiaolu Li · Yuxin Liu · Ying Li · Qiucheng Jia · Sisi Xu · Hongshan Ge

Cell Death Discovery, Published online: 08 September 2026; doi:10.1038/s41420-026-03339-w

Lipotoxicity-induced ER-mitochondrial hypercoupling activates the mtDNA-cGAS-STING-NF-κB axis to drive follicular arrest in metabolically compromised PCOS
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