arXiv:2609.11318v2 Announce Type: replace Abstract: Deep research agents are increasingly capable of web search, tool use, multimodal evidence analysis, and information synthesis. However, existing benchmarks mainly evaluate medium-horizon exploration and rarely test whether agents can sustain long, dependency-heavy research processes. We introduce Mr. LHDR (Multimodal real-world Long-Horizon Deep Research), a benchmark for evaluating real-world deep research over long, irreducible chains of interdependent evidence across eight categories. Each question is constructed from a hidden Node-Relation graph and requires an average of 12.1 necessary intermediate conclusions with a mean dependency depth of 10.4 before reaching a short, unique, and verifiable answer. Questions incorporate multimodal evidence, including images, maps, PDFs, logos, charts, tables, and video frames, with at least one non-text element that changes the reasoning state. Mr. LHDR evaluates both final answers and the correctness of intermediate conclusions under annotated dependencies. We evaluate general models, deep research systems, and agent frameworks using Overall Accuracy (OA), Strict Accuracy (SA), Checklist Score (CS), and Dependency-Aware Checklist Score (DACS). Results show that even the strongest system achieves only 43.1% OA and 34.3% SA, indicating that final-answer accuracy substantially overestimates complete research success. Removing images reduces DACS by 12.6 points, demonstrating the importance of multimodal evidence, while SA consistently declines as reasoning chains become longer. These findings reveal sustained, dependency-consistent evidence integration, rather than isolated fact retrieval, as a key bottleneck for current deep research agents.

arXiv:2604.23580v2 Announce Type: replace-cross Abstract: Translating natural-language descriptions of physical phenomena into executable simulation code requires both programming expertise and physical reasoning. Current large language models (LLMs) lack this combination: they frequently produce code that runs but simulates the wrong physics. We introduce PhysCodeBench, the first benchmark for this task, with 1,200 expert-validated examples spanning four physical domains. Its evaluation suite, PhysCodeEval, goes beyond executability and visual fidelity to measure physical correctness directly from the engine state via conservation-law residuals and expert-written assertions, and supports cross-engine evaluation to disentangle physics reasoning from API fluency. As a reference method, we propose the Self-Corrective Multi-Agent Refinement Framework (SMRF), which decouples physics-aware error correction from code generation through specialized agents. This design is motivated by our finding that targeted correction, rather than generic iterative refinement, is the key driver of physical accuracy. SMRF nearly triples the physical-assertion pass rate of the best proprietary baseline (70.6\% vs.\ 23.8\%) and retains its advantage under cross-engine transfer.

Oncogene, Published online: 11 September 2026; doi:10.1038/s41388-026-03979-3

Propionyl-CoA catabolism is a metabolic gatekeeper for fatty acid oxidation in pancreatic cancer