arXiv:2609.12712v1 Announce Type: cross Abstract: Relational table learning has recently emerged as an important research direction for modeling multiple tables connected through primary key-foreign key (PK-FK) relationships. Despite recent advances, a principled modeling framework tailored to this task remains underexplored. In this paper, we propose Intra-Inter Relational Table Learning (InRTL), a unified framework that explicitly models dependencies both within and across relational tables. Specifically, InRTL formalizes two complementary interaction patterns: intra-table interactions, describing associations among rows within the same table, and inter-table interactions, describing dependencies between rows across PK-FK-linked tables. To model these dependencies, we develop a column-aware table encoder to generate initial row representations, followed by Transformer-based self-attention and cross-attention modules for intra-table and inter-table learning, respectively. To further improve scalability, InRTL incorporates linearized attention and heterogeneous graph neural networks to simplify the self-attention and cross-attention operations. Extensive experiments on ten datasets covering 24 real-world tasks demonstrate the effectiveness of our approach. Code is available at https://github.com/W1nterFloW/InRTL.

arXiv:2609.03753v3 Announce Type: replace Abstract: Cumulative culture enables humans to preserve, reuse, and extend knowledge and skills across experiences and generations. Inspired by this principle, we introduce \textit{SimSkill}, a self-evolving agent built around the Simulation of Urban MObility (SUMO) traffic simulator. SimSkill continually identifies capability gaps, generates and solves environment-grounded tasks, verifies solutions through an action--critic loop, and consolidates experience into episodic, procedural, and semantic memory. Through autonomous exploration, it builds a library of reusable skills and knowledge spanning major stages of the traffic-simulation workflow. We evaluate SimSkill on two held-out benchmarks across three backbone LLMs, with each result independently verified. It improves verified success by up to 25 percentage points, and ablations show complementary contributions from procedural and semantic memory. Its benefits remain backbone- and budget-dependent, as memory does not improve every model or uniformly reduce inference cost. More broadly, SimSkill illustrates a natural-language-centered design paradigm for LLM-based agent systems. Its high-level control logic, operating principles, and accumulated knowledge are expressed in natural language, while an LLM integrates them with executable tools and code to realize precise and reproducible execution. All code and experimental data are publicly available at https://github.com/qiliuchn/SimSkill-V1.

Nature Cancer, Published online: 11 September 2026; doi:10.1038/s43018-026-01236-w

Zheng et al. describe how hypoxia-induced methylmalonate semialdehyde dehydrogenase lactylation promotes acyl-CoA synthetase long-chain family member 4 propionylation and degradation, thereby suppressing ferroptosis induced by chemotherapy, and develop a blocking peptide that increased chemotherapy efficacy in pancreatic ductal adenocarcinoma.