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Toward Robust Personalized Alignment for LLMs: Mitigating Persona Drift in Multi-Turn Dialogue

arXiv:2609.12373v1 Announce Type: new Abstract: Persona drift remains a central challenge for personalized language models, as user profiles evolve over long interactions rather than remain permanently fixed. Models must therefore revise persistent persona states when preferences genuinely change, while avoiding updates driven by transient, ambiguous, or unresolved observations. We propose CORE, which separates turn-local evidence from persistent persona-state revision and selectively updates grounded user preferences through uncertainty-aware belief revision. We also introduce PERSIST, a held-out post-anchor benchmark for persona-state robustness under sequential interaction stress, covering ambiguity, conflict, and controlled social influence. Across ALOE, PersonaChat, and PERSIST, CORE improves personalized alignment and robustness, with complementary gains in normalized closed-slot state fidelity. Human evaluation and mechanistic controls further support explicit update control beyond stronger generation or persistent memory alone.
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EvoRS: On-Policy Self-Evolution of Reward Systems for Open-Ended Reinforcement Learning

arXiv:2609.12459v1 Announce Type: new Abstract: Open-ended reinforcement learning often relies on rubric-based rewards for tasks without directly verifiable answers. Yet the policy and reward system form a dynamic feedback loop: as the policy optimizes the current reward, an initially useful reward system may become unreliable due to reward hacking or reduced response discriminability. The reward system should therefore evolve rather than remain fixed during training. Existing dynamic-rubric methods adapt evaluation criteria, but reward failures can also arise from scoring mechanisms or signal composition. We introduce EvoRS, a self-evolving RL framework that evolves the reward system from on-policy experience, representing it as an executable Reward-DAG. Specifically, an agentic designer updates this system from on-policy rollouts and reward traces to maintain train-time reliability. Across writing and roleplay, EvoRS achieves the best quality under all three judges, outperforming the policy by \(2.107\) and \(4.767\) points, respectively, while reducing reward hacking and coverage failures and preserving reward informativeness. Ablations confirm that a comprehensive fixed reward system cannot remain reliable in open-ended tasks and must evolve throughout training.
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When Does AI Augment Work? A Workflow-Level Framework for Human-Agent Collaboration

arXiv:2609.12482v1 Announce Type: new Abstract: We aim to characterise the value of artificial intelligence in the workplace. Current studies largely measure this value in terms of the current automation capabilities and public adoption of AI. However, such metrics ignore the greater impacts of human--agent collaboration in transforming the nature of work. To account for this, we must expand the scope of our analysis beyond atomised tasks of today, and instead focus on how AI can augment entire workflows of the future. To ground this analysis, we establish a precise definition of AI augmentation comprising six conditions, spanning durable net value, meaningful human control, accountability and recovery, and long-term human development through learning, career pathways, and job purpose. We elaborate on these conditions and apply the framework in a case study of AI-mediated social surveys. We conclude by outlining how organisations, researchers, and government leaders can use this framework to make sense of the future of work.
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Circular RNA MCM3 recruits USP49 to stabilize PTBP1 and promote cisplatin resistance in cervical squamous cell carcinoma

Oncogene, Published online: 12 September 2026; doi:10.1038/s41388-026-03988-2

Circular RNA MCM3 recruits USP49 to stabilize PTBP1 and promote cisplatin resistance in cervical squamous cell carcinoma
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CircRHBDD1(4,5) drives malignant progression of oral squamous cell carcinoma by enhancing DKK1 mRNA stability through facilitating m<sup>6</sup>A-dependent IGF2BP2 binding

Oncogene, Published online: 11 September 2026; doi:10.1038/s41388-026-03986-4

CircRHBDD1(4,5) drives malignant progression of oral squamous cell carcinoma by enhancing DKK1 mRNA stability through facilitating m6A-dependent IGF2BP2 binding
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