Nature Cancer, Published online: 01 September 2026; doi:10.1038/s43018-026-01220-4Chen et al. have developed SlideChat, a multimodal generative artificial intelligence assistant, which they benchmark on 27 pathology tasks across 33 cancer types. Expert pathologists rated the assistant as clinically relevant and accurate.

Oncogene, Published online: 31 August 2026; doi:10.1038/s41388-026-03974-8Frequently amplified SHANK2 promotes esophageal squamous cell carcinoma progression through the DVL/YAP axis

Nature Cancer, Published online: 25 August 2026; doi:10.1038/s43018-026-01241-zAuthor Correction: Low-protein diet enhances antitumor immunity in pancreatic cancer through microbiota-derived UDP-galactose

Li et al. developed a ferritin aggregation cell engager that helps CAR T cells better recognize and attack leukemia cells without re-engineering the CAR itself. This versatile platform overcomes antigen modulation and enables combination with chemotherapy.

Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10264-6Androgen activity in the male embryonic hindbrain prolongs hindbrain differentiation in male individuals and drives sex differences in the incidence and prognosis of posterior fossa type A (PFA) ependymoma, an aggressive childhood brain tumour.

Cell Death Discovery, Published online: 12 March 2026; doi:10.1038/s41420-026-02996-1Harnessing pyroptosis in breast cancer therapy: immunological mechanisms and emerging biomaterial strategies