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Received β€” 27 May 2026 ⏭ Journals

Mapping convergent regulators of melanoma drug resistance by PerturbFate

βœ‡Nature - Issue - nature.com science feeds
By: Zihan Xu Β· Ziyu Lu Β· Aileen Ugurbil Β· Abdulraouf Abdulraouf Β· Andrew Liao Β· Jianxiang Zhang Β· Wei Zhou Β· Junyue Cao
15 April 2026 at 08:00

Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10367-0

PerturbFate is a high-throughput, cost-effective, single-cell platform that systematically profiles CRISPR interference perturbations to reveal common regulatory nodes and convergent phenotypic states across diverse genetic alterations linked to vemurafenib resistance in melanoma cells.
Received β€” 2 April 2026 ⏭ Journals

Targeting FTO shows therapeutic potential in esophageal squamous cell carcinoma by modulating microRNA biogenesis

βœ‡Oncogene - Issue - nature.com science feeds
By: Wei Zhou Β· Chunyan Wang Β· Changhao Li Β· Pengxiang Chen Β· Yuchen Liu Β· Hongyuan Mao Β· Pengfei Zhu Β· Yuxiao Gong Β· Yufeng Cheng Β· Lin Zhang
1 April 2026 at 08:00

Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03754-4

Targeting FTO shows therapeutic potential in esophageal squamous cell carcinoma by modulating microRNA biogenesis
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