Nature - Issue - nature.com science feeds
Satellite imagery reveals increasing volatility in human night-time activity Tian Li · Zhuosen Wang · Christopher C. M. Kyba · Miguel O. Román · Karen C. Seto · Yun Yang · Shi Qiu · Theres Kuester · Michail Fragkias · Xiang Chen · Thomas H. Meyer · Chadwick D. Rittenhouse · Xiaonan Tai · Mari Cullerton · Falu Hong · Ashley Grinstead · Kexin Song · Ji Won Suh · Xiucheng Yang · Virginia L. Kalb · Chengbin Deng · Zhe Zhu
Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10260-wDaily satellite data reveal that Earth’s artificial lights at night are highly volatile, with frequent brightening and dimming between 2014 and 2022.
8 April 2026 at 08:00

Satellite imagery reveals increasing volatility in human night-time activity

Nature - Issue - nature.com science feeds

By: Tian Li · Zhuosen Wang · Christopher C. M. Kyba · Miguel O. Román · Karen C. Seto · Yun Yang · Shi Qiu · Theres Kuester · Michail Fragkias · Xiang Chen · Thomas H. Meyer · Chadwick D. Rittenhouse · Xiaonan Tai · Mari Cullerton · Falu Hong · Ashley Grinstead · Kexin Song · Ji Won Suh · Xiucheng Yang · Virginia L. Kalb · Chengbin Deng · Zhe Zhu

8 April 2026 at 08:00

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10260-w

Daily satellite data reveal that Earth’s artificial lights at night are highly volatile, with frequent brightening and dimming between 2014 and 2022.

Cell
Metabolite-gated vascular contractility switch: OXGR1 activation mechanism enables agonist therapy for rosacea erythema Wenqin Xiao · Yan Zhu · Xinjie Tang · Kongkai Zhu · Weifeng Zhang · Mengting Chen · Kui Cai · San Xu · Zheng Wu · Mei Wang · Jiayi Liu · Linglong Long · Zixin Tan · Aike Wu · Songqi Zhou · Zhixiang Zhao · Yan Tang · Yingxue Huang · Ben Wang · Fangfen Liu · Qian Wang · Fan Yang · Dan Jian · Wei Shi · Hongfu Xie · Xiang Chen · Lulu Guo · Zhili Deng · Jinpeng Sun · Ji Li
Xiao et al. identify α-KG as a rosacea-associated metabolite that activates the OXGR1-Gq-MYL9 axis in the vascular smooth muscle cells to boost contractility and suppress pathological vasodilation underlying erythema. Cryo-EM reveals a bipartite-acid pocket of OXGR1 that enables structure-guided development of A-1, a selective agonist that alleviates erythema in rosacea-like models.
5 March 2026 at 08:00

Metabolite-gated vascular contractility switch: OXGR1 activation mechanism enables agonist therapy for rosacea erythema

Cell

By: Wenqin Xiao · Yan Zhu · Xinjie Tang · Kongkai Zhu · Weifeng Zhang · Mengting Chen · Kui Cai · San Xu · Zheng Wu · Mei Wang · Jiayi Liu · Linglong Long · Zixin Tan · Aike Wu · Songqi Zhou · Zhixiang Zhao · Yan Tang · Yingxue Huang · Ben Wang · Fangfen Liu · Qian Wang · Fan Yang · Dan Jian · Wei Shi · Hongfu Xie · Xiang Chen · Lulu Guo · Zhili Deng · Jinpeng Sun · Ji Li

5 March 2026 at 08:00

Xiao et al. identify α-KG as a rosacea-associated metabolite that activates the OXGR1-Gq-MYL9 axis in the vascular smooth muscle cells to boost contractility and suppress pathological vasodilation underlying erythema. Cryo-EM reveals a bipartite-acid pocket of OXGR1 that enables structure-guided development of A-1, a selective agonist that alleviates erythema in rosacea-like models.

Oncogene - Issue - nature.com science feeds
Targeting FTO shows therapeutic potential in esophageal squamous cell carcinoma by modulating microRNA biogenesis Wei Zhou · Chunyan Wang · Changhao Li · Pengxiang Chen · Yuchen Liu · Hongyuan Mao · Pengfei Zhu · Yuxiao Gong · Yufeng Cheng · Lin Zhang
Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03754-4Targeting FTO shows therapeutic potential in esophageal squamous cell carcinoma by modulating microRNA biogenesis
1 April 2026 at 08:00

Targeting FTO shows therapeutic potential in esophageal squamous cell carcinoma by modulating microRNA biogenesis

Oncogene - Issue - nature.com science feeds

By: Wei Zhou · Chunyan Wang · Changhao Li · Pengxiang Chen · Yuchen Liu · Hongyuan Mao · Pengfei Zhu · Yuxiao Gong · Yufeng Cheng · Lin Zhang

1 April 2026 at 08:00

Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03754-4

Targeting FTO shows therapeutic potential in esophageal squamous cell carcinoma by modulating microRNA biogenesis

Normal view