❌

Normal view

The Effectiveness of Digital Intervention on Psychological Resilience in Postoperative Breast Cancer Patients During Chemotherapy Intervals: Quasi-Experimental Study

Background: Patients with breast cancer during postoperative chemotherapy intervals commonly experience psychological distress and reduced resilience while recovering at home. Digital mindfulness interventions may provide accessible psychological support during this vulnerable period; however, evidence regarding tailored interventions for postoperative patients with breast cancer during chemotherapy intervals remains limited. Objective: This study aimed to examine the effectiveness of a digital intervention on psychological resilience in postoperative patients with breast cancer during chemotherapy intervals. Methods: A quasi-experimental study with repeated measures was conducted from October 2021 to June 2022. A total of 80 eligible participants were recruited from the Department of Breast Surgery at a tertiary hospital in Zhejiang Province, China, and 71 completed the study. The control group received routine discharge instructions and nursing follow-ups, whereas the intervention group additionally received an 8-week digital psychological resilience intervention. Outcomes were assessed at baseline (T0), 3 months post intervention (T1), and 6 months post intervention (T2). The measures included the Connor-Davidson Resilience Scale (CD-RISC), Hospital Anxiety and Depression Scale (HADS), Social Support Rating Scale (SSRS), Breast Cancer Survivor Self-Efficacy Scale (BCSSS), and Functional Assessment of Cancer Therapy-Breast (FACT-B). Independent-samples tests, chi-square tests, and repeated-measures ANOVA were performed using SPSS (version 26.0; IBM Corp). Results: No statistically significant baseline differences were observed between the two groups in the outcome measures. At T1, the intervention group had higher CD-RISC scores than the control group (mean 67.58, SD 11.41 vs mean 62.09, SD 10.18; =.036) and higher BCSSS scores (mean 42.36, SD 3.59 vs mean 39.23, SD 4.90; =.003). However, these between-group differences were no longer statistically significant at T2 (>.05). Significant time effects and group×time interaction effects were observed for both psychological resilience and self-efficacy (.05), although both scales showed significant time effects (

A clinically-oriented foundation model for intraoperative pathology

Nature Medicine, Published online: 10 September 2026; doi:10.1038/s41591-026-04703-0

CRISP, a vision-based pathology foundation model developed exclusively from frozen section slides, supports treatment decision-making throughout the surgical workflow with superior performance to current foundation models and extensive validation, including in a prospective cohort.

Advancing solar and wind penetration in China through energy complementarity

Nature, Published online: 20 May 2026; doi:10.1038/s41586-026-10570-z

Using high-resolution satellite imagery combined with a deep-learning-based framework to build a national energy inventory enables a data-driven assessment of solar–wind complementarity strategies to reduce power variability and enhance renewable energy penetration across China.

EBV strain interacts with host HLA to drive nasopharyngeal carcinoma risk

Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10416-8

A genome-to-genome association study identifies host and viral risk factors that interact to drive nasopharyngeal carcinoma endemicity in southern China.

Engineered immunosuppressive dendritic cells protect against cardiac remodelling

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10346-5

Lesion-targeted immune modulation is a feasible strategy to control cardiac fibrosis, and engineered dendritic cells are a promising therapeutic platform for treating cardiac remodelling and heart failure.

LINC-AC092535.5 regulates MICAL2 mRNA level to inhibit p53-mediated ferroptosis in nasopharyngeal carcinoma

Oncogene, Published online: 14 March 2026; doi:10.1038/s41388-026-03714-y

LINC-AC092535.5 regulates MICAL2 mRNA level to inhibit p53-mediated ferroptosis in nasopharyngeal carcinoma
❌