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Normal view

Deciphering functional intra-tumoral heterogeneity in BRAF<sup>V600E</sup>-driven mouse thyroid cancer reveals EMT trajectory and metabolic remodeling

Oncogene, Published online: 04 April 2026; doi:10.1038/s41388-026-03742-8

Deciphering functional intra-tumoral heterogeneity in BRAFV600E-driven mouse thyroid cancer reveals EMT trajectory and metabolic remodeling

Spliceosomal component SNRPE drives cell proliferation by regulating CTP synthase 1 mRNA splicing in ovarian cancer

Oncogene, Published online: 04 April 2026; doi:10.1038/s41388-026-03764-2

Spliceosomal component SNRPE drives cell proliferation by regulating CTP synthase 1 mRNA splicing in ovarian cancer

HoloTrauma 3X Triadic AI Co reasoning for robot assisted emergency maxillofacial reconstruction

npj Digital Medicine, Published online: 04 April 2026; doi:10.1038/s41746-026-02573-x

HoloTrauma 3X Triadic AI Co reasoning for robot assisted emergency maxillofacial reconstruction

Developing psychosocial phenotypes to understand engagement with digital health technologies for heart failure

npj Digital Medicine, Published online: 04 April 2026; doi:10.1038/s41746-026-02571-z

Developing psychosocial phenotypes to understand engagement with digital health technologies for heart failure

New model, old risks: sociodemographic bias and adversarial hallucinations vulnerability in GPT-5

npj Digital Medicine, Published online: 04 April 2026; doi:10.1038/s41746-026-02584-8

We re-evaluated GPT-5 using our published pipelines: 500 emergency vignettes across 32 sociodemographic labels for bias, and adversarial prompts with fabricated details. GPT-5 showed no measurable improvement over GPT-4o in sociodemographic-linked decision variation, with several LGBTQIA+ groups flagged for mental-health screening in 100% of cases. Adversarial hallucination rates were higher (65% vs 53% for GPT-4o); a mitigation prompt reduced this to 7.67%.
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