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ATP2B4 driven chromatin compaction exacerbates pancreatic cancer radiotherapy resistance

Cell Death Discovery, Published online: 25 May 2026; doi:10.1038/s41420-026-03142-7

ATP2B4 driven chromatin compaction exacerbates pancreatic cancer radiotherapy resistance

Advancing solar and wind penetration in China through energy complementarity

Nature, Published online: 20 May 2026; doi:10.1038/s41586-026-10570-z

Using high-resolution satellite imagery combined with a deep-learning-based framework to build a national energy inventory enables a data-driven assessment of solar–wind complementarity strategies to reduce power variability and enhance renewable energy penetration across China.

CD300ld on pathologically activated neutrophils promotes tumor immune suppression by binding phosphatidylserine on CD8<sup>+</sup> T cells

Nature Cancer, Published online: 15 May 2026; doi:10.1038/s43018-026-01169-4

Zhao and colleagues show that CD300ld, upregulated in pathologically activated neutrophils, mediates contact-dependent suppression of cytotoxic CD8+ T cells by binding to phosphatidylserine, inhibiting antitumor immune responses.

Linear RAG scanning mediates editing of Igκ variable region repertoires

Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10362-5

Studies explaining the secondary Igk recombination mechanism are described and Cer/Sis deletion and/or displacement is implicated as a developmental switch converting the rearrangement mechanisms from two-loop-based diffusional primary Igk into one-loop-based linear scanning secondary mechanisms.
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