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Sirt1 sustains Sonic hedgehog signaling to promote medulloblastoma progression through regulating Gli3 processing

Oncogene, Published online: 18 April 2026; doi:10.1038/s41388-026-03781-1

Sirt1 sustains Sonic hedgehog signaling to promote medulloblastoma progression through regulating Gli3 processing

EBV strain interacts with host HLA to drive nasopharyngeal carcinoma risk

Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10416-8

A genome-to-genome association study identifies host and viral risk factors that interact to drive nasopharyngeal carcinoma endemicity in southern China.

Composable neural emulators accelerate thermoelectric generator design

Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10223-1

A composable neural network emulator is described for speeding up thermoelectric generator design, demonstrating the ability to predict generator performance with >99% accuracy while taking only 0.01% of the time compared with commercial finite-element solvers.
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