M⁶A-dependent upregulation of ZNF460 promotes epithelial-mesenchymal transition and metastasis of gastric cancer through a histone modification-mediated positive feedback loop

Oncogene - Issue - nature.com science feeds
Strand-asymmetric G-runs and G4s downstream of TSS modulate tumor suppressor gene transcription Dan Huang · Xiaoting Zhang · Xiansong Wang · Ziheng Huang · Judeng Zeng · Xiaodong Liu · Likai Tan · Lin Zhang · Zhenxing Guo · Tony Gin · Jun Yu · Kwok M. Ho · Matthew Tak Vai Chan · Huarong Chen · William Ka Kei Wu
Oncogene, Published online: 02 April 2026; doi:10.1038/s41388-026-03761-5Strand-asymmetric G-runs and G4s downstream of TSS modulate tumor suppressor gene transcription
2 April 2026 at 08:00

Strand-asymmetric G-runs and G4s downstream of TSS modulate tumor suppressor gene transcription

Oncogene - Issue - nature.com science feeds

By: Dan Huang · Xiaoting Zhang · Xiansong Wang · Ziheng Huang · Judeng Zeng · Xiaodong Liu · Likai Tan · Lin Zhang · Zhenxing Guo · Tony Gin · Jun Yu · Kwok M. Ho · Matthew Tak Vai Chan · Huarong Chen · William Ka Kei Wu

2 April 2026 at 08:00

Oncogene, Published online: 02 April 2026; doi:10.1038/s41388-026-03761-5

Oncogene - Issue - nature.com science feeds
Correction: The multifunctional RNA helicase DDX39A drives glioblastoma progression by modulating WISP1 alternative splicing that induces an immunosuppressive macrophage polarization Yan Zhang · Zhiwei Xue · Naibin Zhang · Yuehua Zhu · YanZhao Wu · Meilin Lv · Zhihan Zhang · Feiyu Mu · Wenchen Xing · Ziyi Tang · Chunjie Wang · Zhiyi Xue · Wenjing Zhou · Xiaofei Liu · Xingang Li · Rolf Bjerkvig · Bin Huang · Mingzhi Han · Jian Wang · Donghai Wang
Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03756-2Correction: The multifunctional RNA helicase DDX39A drives glioblastoma progression by modulating WISP1 alternative splicing that induces an immunosuppressive macrophage polarization
1 April 2026 at 08:00

Correction: The multifunctional RNA helicase DDX39A drives glioblastoma progression by modulating WISP1 alternative splicing that induces an immunosuppressive macrophage polarization

Oncogene - Issue - nature.com science feeds

By: Yan Zhang · Zhiwei Xue · Naibin Zhang · Yuehua Zhu · YanZhao Wu · Meilin Lv · Zhihan Zhang · Feiyu Mu · Wenchen Xing · Ziyi Tang · Chunjie Wang · Zhiyi Xue · Wenjing Zhou · Xiaofei Liu · Xingang Li · Rolf Bjerkvig · Bin Huang · Mingzhi Han · Jian Wang · Donghai Wang

1 April 2026 at 08:00

Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03756-2

Correction: The multifunctional RNA helicase DDX39A drives glioblastoma progression by modulating WISP1 alternative splicing that induces an immunosuppressive macrophage polarization

Oncogene - Issue - nature.com science feeds
LDHA-driven lactate metabolism promotes MDSC activation and immunosuppressive microenvironment in prostate cancer Xiyi Wei · Xiao Li · Yitong Pan · Yuwei Zhang · Da Zhong · Weiyu Kong · Yue Wang · Zijie Yu · Wenchuan Shao · Yuxiang Dong · Silin Jiang · Zige Qiu · Xiang Li · Yize Li · Shouyong Gu · Chenxi Tian · Chao Qin · Qingyi Zhu · Ninghan Feng · Ninghong Song · Bing Yao · Zhou Yang
Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03737-5LDHA-driven lactate metabolism promotes MDSC activation and immunosuppressive microenvironment in prostate cancer
1 April 2026 at 08:00

LDHA-driven lactate metabolism promotes MDSC activation and immunosuppressive microenvironment in prostate cancer

Oncogene - Issue - nature.com science feeds

By: Xiyi Wei · Xiao Li · Yitong Pan · Yuwei Zhang · Da Zhong · Weiyu Kong · Yue Wang · Zijie Yu · Wenchuan Shao · Yuxiang Dong · Silin Jiang · Zige Qiu · Xiang Li · Yize Li · Shouyong Gu · Chenxi Tian · Chao Qin · Qingyi Zhu · Ninghan Feng · Ninghong Song · Bing Yao · Zhou Yang

1 April 2026 at 08:00

Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03737-5

LDHA-driven lactate metabolism promotes MDSC activation and immunosuppressive microenvironment in prostate cancer

Oncogene - Issue - nature.com science feeds
Targeting FTO shows therapeutic potential in esophageal squamous cell carcinoma by modulating microRNA biogenesis Wei Zhou · Chunyan Wang · Changhao Li · Pengxiang Chen · Yuchen Liu · Hongyuan Mao · Pengfei Zhu · Yuxiao Gong · Yufeng Cheng · Lin Zhang
Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03754-4Targeting FTO shows therapeutic potential in esophageal squamous cell carcinoma by modulating microRNA biogenesis
1 April 2026 at 08:00

Targeting FTO shows therapeutic potential in esophageal squamous cell carcinoma by modulating microRNA biogenesis

Oncogene - Issue - nature.com science feeds

By: Wei Zhou · Chunyan Wang · Changhao Li · Pengxiang Chen · Yuchen Liu · Hongyuan Mao · Pengfei Zhu · Yuxiao Gong · Yufeng Cheng · Lin Zhang

1 April 2026 at 08:00

Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03754-4

Targeting FTO shows therapeutic potential in esophageal squamous cell carcinoma by modulating microRNA biogenesis

Oncogene - Issue - nature.com science feeds
X-linked cancer-associated polypeptide (XCP) from lncRNA1456 modulates PHF8 histone demethylase activity to regulate the epigenome, gene expression, and cellular pathways in breast cancer Shrikanth S. Gadad · Cristel V. Camacho · Xuan Gong · Micah Thornton · Venkat S. Malladi · Anusha Nagari · Aishwarya Sundaresan · Tulip Nandu · Sneh Koul · Yan Peng · W. Lee Kraus
Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03740-wX-linked cancer-associated polypeptide (XCP) from lncRNA1456 modulates PHF8 histone demethylase activity to regulate the epigenome, gene expression, and cellular pathways in breast cancer
1 April 2026 at 08:00

X-linked cancer-associated polypeptide (XCP) from lncRNA1456 modulates PHF8 histone demethylase activity to regulate the epigenome, gene expression, and cellular pathways in breast cancer

Oncogene - Issue - nature.com science feeds

By: Shrikanth S. Gadad · Cristel V. Camacho · Xuan Gong · Micah Thornton · Venkat S. Malladi · Anusha Nagari · Aishwarya Sundaresan · Tulip Nandu · Sneh Koul · Yan Peng · W. Lee Kraus

1 April 2026 at 08:00

Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03740-w

X-linked cancer-associated polypeptide (XCP) from lncRNA1456 modulates PHF8 histone demethylase activity to regulate the epigenome, gene expression, and cellular pathways in breast cancer

Oncogene - Issue - nature.com science feeds
STAT3-mediated transactivation of NOVA2 promotes lung adenocarcinoma metastasis by splicing SMAD4 Shengjie Wang · Xin Tong · Runfeng Sun · Xinyi Xia · Donglai Chen · Zhao Wang · Hao Shi · Chenzhuo Wu · Xiaoxiao Guo · Die Hu · Ersuo Jin · Hong-Tao Zhang
Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03752-6STAT3-mediated transactivation of NOVA2 promotes lung adenocarcinoma metastasis by splicing SMAD4
1 April 2026 at 08:00

STAT3-mediated transactivation of NOVA2 promotes lung adenocarcinoma metastasis by splicing SMAD4

Oncogene - Issue - nature.com science feeds

By: Shengjie Wang · Xin Tong · Runfeng Sun · Xinyi Xia · Donglai Chen · Zhao Wang · Hao Shi · Chenzhuo Wu · Xiaoxiao Guo · Die Hu · Ersuo Jin · Hong-Tao Zhang

1 April 2026 at 08:00

Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03752-6

STAT3-mediated transactivation of NOVA2 promotes lung adenocarcinoma metastasis by splicing SMAD4

Oncogene - Issue - nature.com science feeds
Fusobacterium nucleatum drives colorectal cancer progression through the circPTBP3/miR-760/PUM1 axis Chunmin Li · Qianqian Liu · Hangchang Shen · Tianhui Zou · Linna Fu · Yingxuan Chen
Oncogene, Published online: 31 March 2026; doi:10.1038/s41388-026-03746-4Fusobacterium nucleatum drives colorectal cancer progression through the circPTBP3/miR-760/PUM1 axis
31 March 2026 at 08:00

Fusobacterium nucleatum drives colorectal cancer progression through the circPTBP3/miR-760/PUM1 axis

Oncogene - Issue - nature.com science feeds

By: Chunmin Li · Qianqian Liu · Hangchang Shen · Tianhui Zou · Linna Fu · Yingxuan Chen

31 March 2026 at 08:00

Oncogene, Published online: 31 March 2026; doi:10.1038/s41388-026-03746-4

Fusobacterium nucleatum drives colorectal cancer progression through the circPTBP3/miR-760/PUM1 axis

Oncogene - Issue - nature.com science feeds
Dual function of DOT1L suppresses tumor cell-intrinsic immunogenicity in hepatocellular carcinoma Siyuan Xu · Ruijie Gong · Songchen Liu · Jianhua Wang · Yijie Shen · Chuxuan Peng · Qin Feng · Min Luo · Fei Lan · Jia Fan · Jiabin Cai · Xianjiang Lan
Oncogene, Published online: 31 March 2026; doi:10.1038/s41388-026-03744-6Dual function of DOT1L suppresses tumor cell-intrinsic immunogenicity in hepatocellular carcinoma
31 March 2026 at 08:00

Dual function of DOT1L suppresses tumor cell-intrinsic immunogenicity in hepatocellular carcinoma

Oncogene - Issue - nature.com science feeds

By: Siyuan Xu · Ruijie Gong · Songchen Liu · Jianhua Wang · Yijie Shen · Chuxuan Peng · Qin Feng · Min Luo · Fei Lan · Jia Fan · Jiabin Cai · Xianjiang Lan

31 March 2026 at 08:00

Oncogene, Published online: 31 March 2026; doi:10.1038/s41388-026-03744-6

Dual function of DOT1L suppresses tumor cell-intrinsic immunogenicity in hepatocellular carcinoma

Oncogene - Issue - nature.com science feeds
Editorial Expression of Concern: GRP78 regulates clusterin stability, retrotranslocation and mitochondrial localization under ER stress in prostate cancer N. Li · A. Zoubeidi · E. Beraldi · M. E. Gleave
Oncogene, Published online: 30 March 2026; doi:10.1038/s41388-026-03770-4Editorial Expression of Concern: GRP78 regulates clusterin stability, retrotranslocation and mitochondrial localization under ER stress in prostate cancer
30 March 2026 at 08:00

Editorial Expression of Concern: GRP78 regulates clusterin stability, retrotranslocation and mitochondrial localization under ER stress in prostate cancer

Oncogene - Issue - nature.com science feeds

By: N. Li · A. Zoubeidi · E. Beraldi · M. E. Gleave

30 March 2026 at 08:00

Oncogene, Published online: 30 March 2026; doi:10.1038/s41388-026-03770-4

Editorial Expression of Concern: GRP78 regulates clusterin stability, retrotranslocation and mitochondrial localization under ER stress in prostate cancer

Oncogene - Issue - nature.com science feeds
Loss of ABCA3 disrupts lipid balance and leads to AMPK-dependent suppression of SREBP1 in glioblastoma stem cells Jun-Kyum Kim · Min Gi Park · Seok Won Ham · Seunghyun Yoon · Sua Kim · Junseok Jang · Hyejin Kim · Nayoung Hong · Jong Min Park · Cheol Gyu Park · Min Ji Park · Sang-Hun Choi · Jung Yun Kim · Hee-Young Jeon · Sunyoung Seo · Seon Yong Lee · Yeri Lee · Hee Jin Cho · Minseo Gwak · Eun-Jung Kim · Kiyoung Eun · Yong Jae Shin · Do-Hyun Nam · Se Hoon Kim · Seung Jun Yoo · Hyunggee Kim
Oncogene, Published online: 25 March 2026; doi:10.1038/s41388-026-03736-6Loss of ABCA3 disrupts lipid balance and leads to AMPK-dependent suppression of SREBP1 in glioblastoma stem cells
25 March 2026 at 08:00

Loss of ABCA3 disrupts lipid balance and leads to AMPK-dependent suppression of SREBP1 in glioblastoma stem cells

Oncogene - Issue - nature.com science feeds

By: Jun-Kyum Kim · Min Gi Park · Seok Won Ham · Seunghyun Yoon · Sua Kim · Junseok Jang · Hyejin Kim · Nayoung Hong · Jong Min Park · Cheol Gyu Park · Min Ji Park · Sang-Hun Choi · Jung Yun Kim · Hee-Young Jeon · Sunyoung Seo · Seon Yong Lee · Yeri Lee · Hee Jin Cho · Minseo Gwak · Eun-Jung Kim · Kiyoung Eun · Yong Jae Shin · Do-Hyun Nam · Se Hoon Kim · Seung Jun Yoo · Hyunggee Kim

25 March 2026 at 08:00

Oncogene, Published online: 25 March 2026; doi:10.1038/s41388-026-03736-6

Loss of ABCA3 disrupts lipid balance and leads to AMPK-dependent suppression of SREBP1 in glioblastoma stem cells

Oncogene - Issue - nature.com science feeds
TRIM21-mediated degradation of HILPDA overcomes anti-PD-1 immunotherapy resistance in breast cancer by limiting PD-L1 palmitoylation Xi Wang · Guangyan Li · Jiaming Wu · Baiyang Fu · Haoyang Zhang · Yichi Chen · Jianjiao Wang · Jianguo Zhang · Xi Chen
Oncogene, Published online: 24 March 2026; doi:10.1038/s41388-026-03728-6TRIM21-mediated degradation of HILPDA overcomes anti-PD-1 immunotherapy resistance in breast cancer by limiting PD-L1 palmitoylation
24 March 2026 at 08:00

TRIM21-mediated degradation of HILPDA overcomes anti-PD-1 immunotherapy resistance in breast cancer by limiting PD-L1 palmitoylation

Oncogene - Issue - nature.com science feeds

By: Xi Wang · Guangyan Li · Jiaming Wu · Baiyang Fu · Haoyang Zhang · Yichi Chen · Jianjiao Wang · Jianguo Zhang · Xi Chen

24 March 2026 at 08:00

Oncogene, Published online: 24 March 2026; doi:10.1038/s41388-026-03728-6

TRIM21-mediated degradation of HILPDA overcomes anti-PD-1 immunotherapy resistance in breast cancer by limiting PD-L1 palmitoylation

Oncogene - Issue - nature.com science feeds
Non-classic deubiquitinase USP13 inhibits bladder cancer metastasis through destabilizing cytoplasmic KDM3A Hongji Hu · Xiangpeng Zhan · Yunqiang Xiong · Ruize Yuan · Yuanzhuo Du · Qianxi Dong · Sheng Li · Biao Guo · Zhongqi Li · Jianhua Feng · Situ Xiong · Jing Xiong · Dongshui Li · Bin Fu · Songhui Xu · Ju Guo
Oncogene, Published online: 24 March 2026; doi:10.1038/s41388-026-03730-yNon-classic deubiquitinase USP13 inhibits bladder cancer metastasis through destabilizing cytoplasmic KDM3A
24 March 2026 at 08:00

Non-classic deubiquitinase USP13 inhibits bladder cancer metastasis through destabilizing cytoplasmic KDM3A

Oncogene - Issue - nature.com science feeds

By: Hongji Hu · Xiangpeng Zhan · Yunqiang Xiong · Ruize Yuan · Yuanzhuo Du · Qianxi Dong · Sheng Li · Biao Guo · Zhongqi Li · Jianhua Feng · Situ Xiong · Jing Xiong · Dongshui Li · Bin Fu · Songhui Xu · Ju Guo

24 March 2026 at 08:00

Oncogene, Published online: 24 March 2026; doi:10.1038/s41388-026-03730-y

Non-classic deubiquitinase USP13 inhibits bladder cancer metastasis through destabilizing cytoplasmic KDM3A

Normal view

Trisomy 8 alters chromatin conformations and activates Y chromosome genes in stem cells to drive a pre-leukemic state

Pre-operative circulating tumor cells predict worse treatment outcome in patients with high-grade serous ovarian cancer

S100A6 promotes liver metastasis by activating FGFR3 signaling in <i>BAP1</i>-deficient uveal melanoma

Deciphering functional intra-tumoral heterogeneity in BRAF<sup>V600E</sup>-driven mouse thyroid cancer reveals EMT trajectory and metabolic remodeling

Spliceosomal component SNRPE drives cell proliferation by regulating CTP synthase 1 mRNA splicing in ovarian cancer

<i>TWIST1</i> mediated transcriptional activation of <i>SPON2</i> drives colorectal cancer peritoneal metastasis through stromal cell signaling network

The role of Rho-associated coiled-coil kinases (ROCK) in cancer

M<sup>6</sup>A-dependent upregulation of ZNF460 promotes epithelial-mesenchymal transition and metastasis of gastric cancer through a histone modification-mediated positive feedback loop

Strand-asymmetric G-runs and G4s downstream of TSS modulate tumor suppressor gene transcription

Correction: The multifunctional RNA helicase DDX39A drives glioblastoma progression by modulating WISP1 alternative splicing that induces an immunosuppressive macrophage polarization

LDHA-driven lactate metabolism promotes MDSC activation and immunosuppressive microenvironment in prostate cancer

Targeting FTO shows therapeutic potential in esophageal squamous cell carcinoma by modulating microRNA biogenesis

X-linked cancer-associated polypeptide (XCP) from <i>lncRNA1456</i> modulates PHF8 histone demethylase activity to regulate the epigenome, gene expression, and cellular pathways in breast cancer

STAT3-mediated transactivation of NOVA2 promotes lung adenocarcinoma metastasis by splicing SMAD4

<i>Fusobacterium nucleatum</i> drives colorectal cancer progression through the <i>circPTBP</i>3/<i>miR-760</i>/<i>PUM1</i> axis

Dual function of DOT1L suppresses tumor cell-intrinsic immunogenicity in hepatocellular carcinoma

Editorial Expression of Concern: GRP78 regulates clusterin stability, retrotranslocation and mitochondrial localization under ER stress in prostate cancer

Loss of <i>ABCA3</i> disrupts lipid balance and leads to AMPK-dependent suppression of <i>SREBP1</i> in glioblastoma stem cells

TRIM21-mediated degradation of HILPDA overcomes anti-PD-1 immunotherapy resistance in breast cancer by limiting PD-L1 palmitoylation

Non-classic deubiquitinase USP13 inhibits bladder cancer metastasis through destabilizing cytoplasmic KDM3A