DHCR24⁺ tumor epithelial cells drive cisplatin resistance in bladder cancer by enhancing cholesterol metabolism to activate lipid raft-associated MAPK signaling

Oncogene - Issue - nature.com science feeds
Liver-specific SIRT1 knockout-induced hyperglycemia promotes spontaneous lung adenocarcinomas through HSF1-MDM2 Yiwei Cao · Jingyi Wei · Qiang Chen · Haitao Wang · Jiao Mu · Shuhan Lu · Menghui Yuan · Mohammed A. El-Magd · Bichan Xu · Ruihong Wang · Peng Yuan
Oncogene, Published online: 24 May 2026; doi:10.1038/s41388-026-03826-5Liver-specific SIRT1 knockout-induced hyperglycemia promotes spontaneous lung adenocarcinomas through HSF1-MDM2
24 May 2026 at 08:00

Liver-specific SIRT1 knockout-induced hyperglycemia promotes spontaneous lung adenocarcinomas through HSF1-MDM2

Oncogene - Issue - nature.com science feeds

By: Yiwei Cao · Jingyi Wei · Qiang Chen · Haitao Wang · Jiao Mu · Shuhan Lu · Menghui Yuan · Mohammed A. El-Magd · Bichan Xu · Ruihong Wang · Peng Yuan

24 May 2026 at 08:00

Oncogene, Published online: 24 May 2026; doi:10.1038/s41388-026-03826-5

Liver-specific SIRT1 knockout-induced hyperglycemia promotes spontaneous lung adenocarcinomas through HSF1-MDM2

Oncogene - Issue - nature.com science feeds
Signals from the bone marrow B cell niches shape pre-leukemic fate in a murine model of B cell acute lymphoblastic leukemia Marjorie C. Delahaye · Simon Léonard · Jeoffrey Pelletier · Jérôme Destin · Florence Bardin · Mourad Ounis · Céline Monvoisin · Naïs Prade · Laurine Gil · Audrey Dauba · Pierre Milpied · Ahmed Amine Khamlichi · Eric Delabesse · Tony Marchand · Cyril Broccardo · Michel Aurrand-Lions · Bastien Gerby · Stéphane JC Mancini
Oncogene, Published online: 23 May 2026; doi:10.1038/s41388-026-03827-4Signals from the bone marrow B cell niches shape pre-leukemic fate in a murine model of B cell acute lymphoblastic leukemia
23 May 2026 at 08:00

Signals from the bone marrow B cell niches shape pre-leukemic fate in a murine model of B cell acute lymphoblastic leukemia

Oncogene - Issue - nature.com science feeds

By: Marjorie C. Delahaye · Simon Léonard · Jeoffrey Pelletier · Jérôme Destin · Florence Bardin · Mourad Ounis · Céline Monvoisin · Naïs Prade · Laurine Gil · Audrey Dauba · Pierre Milpied · Ahmed Amine Khamlichi · Eric Delabesse · Tony Marchand · Cyril Broccardo · Michel Aurrand-Lions · Bastien Gerby · Stéphane JC Mancini

23 May 2026 at 08:00

Oncogene, Published online: 23 May 2026; doi:10.1038/s41388-026-03827-4

Signals from the bone marrow B cell niches shape pre-leukemic fate in a murine model of B cell acute lymphoblastic leukemia

Oncogene - Issue - nature.com science feeds
Lactic acid induces dendritic cell pyroptosis through MCT-1 to promote tumor immune evasion Shengrui Yang · Liyuan Lin · Xiang Zheng · Jie Li · Rong Qin · Yuqing Wu · Jian Xu
Oncogene, Published online: 23 May 2026; doi:10.1038/s41388-026-03825-6Lactic acid induces dendritic cell pyroptosis through MCT-1 to promote tumor immune evasion
23 May 2026 at 08:00

Lactic acid induces dendritic cell pyroptosis through MCT-1 to promote tumor immune evasion

Oncogene - Issue - nature.com science feeds

By: Shengrui Yang · Liyuan Lin · Xiang Zheng · Jie Li · Rong Qin · Yuqing Wu · Jian Xu

23 May 2026 at 08:00

Oncogene, Published online: 23 May 2026; doi:10.1038/s41388-026-03825-6

Lactic acid induces dendritic cell pyroptosis through MCT-1 to promote tumor immune evasion

Oncogene - Issue - nature.com science feeds
GPX8+ cancer-associated fibroblast-derived lactate contributes to lenvatinib resistance by facilitating BRPF1 expression through histone H3 lysine 18 lactylation in hepatocellular carcinoma Qinsi Wan · Jie Li · Mengzhou Guo · Jiahao Hu · Liangliang Bai · Meixia Zhang · Bimin Li · Yuan Fang · Xiaojing Du · Xingxing Zhang · Li Song · Sinuo Chen · Zhuoran Qi · Jinglin Xia · Bei Lv · Mingyan He
Oncogene, Published online: 22 May 2026; doi:10.1038/s41388-026-03711-1GPX8+ cancer-associated fibroblast-derived lactate contributes to lenvatinib resistance by facilitating BRPF1 expression through histone H3 lysine 18 lactylation in hepatocellular carcinoma
22 May 2026 at 08:00

GPX8+ cancer-associated fibroblast-derived lactate contributes to lenvatinib resistance by facilitating BRPF1 expression through histone H3 lysine 18 lactylation in hepatocellular carcinoma

Oncogene - Issue - nature.com science feeds

By: Qinsi Wan · Jie Li · Mengzhou Guo · Jiahao Hu · Liangliang Bai · Meixia Zhang · Bimin Li · Yuan Fang · Xiaojing Du · Xingxing Zhang · Li Song · Sinuo Chen · Zhuoran Qi · Jinglin Xia · Bei Lv · Mingyan He

22 May 2026 at 08:00

Oncogene, Published online: 22 May 2026; doi:10.1038/s41388-026-03711-1

GPX8⁺ cancer-associated fibroblast-derived lactate contributes to lenvatinib resistance by facilitating BRPF1 expression through histone H3 lysine 18 lactylation in hepatocellular carcinoma

Oncogene - Issue - nature.com science feeds
circPARPBP promotes cancer stemness and chemoresistance in triple-negative breast cancer through recruiting SRCAP complex to activate CCL20 transcription Bo Chen · Kang Ma · Wenhuan Zhong · Yunjie Wang · Cheng Long · Xueyan Mao · Hailin Tang · Xudong Zhu · Anli Yang · Peng Liu
Oncogene, Published online: 21 May 2026; doi:10.1038/s41388-026-03819-4circPARPBP promotes cancer stemness and chemoresistance in triple-negative breast cancer through recruiting SRCAP complex to activate CCL20 transcription
21 May 2026 at 08:00

circPARPBP promotes cancer stemness and chemoresistance in triple-negative breast cancer through recruiting SRCAP complex to activate CCL20 transcription

Oncogene - Issue - nature.com science feeds

By: Bo Chen · Kang Ma · Wenhuan Zhong · Yunjie Wang · Cheng Long · Xueyan Mao · Hailin Tang · Xudong Zhu · Anli Yang · Peng Liu

21 May 2026 at 08:00

Oncogene, Published online: 21 May 2026; doi:10.1038/s41388-026-03819-4

circPARPBP promotes cancer stemness and chemoresistance in triple-negative breast cancer through recruiting SRCAP complex to activate CCL20 transcription

Oncogene - Issue - nature.com science feeds
NDRG2 orchestrates circadian clock stability to suppress tumorigenesis and potentiate oxaliplatin response in colorectal cancer Ruikai Li · Ruxin Ding · Hanjun Dan · Kunli Du · Gaozan Zheng · Siyuan Wang · Lili Duan · Pengfei Wang · Liangliang Shen · Lin Feng · Pan Zhao · Jiajia Wang · Dan Feng · Fengsu Wu · Yumao Yang · Ziting Zhou · Liaoran Niu · Weidong Wang · Xinyu Qiao · Jianting Yang · Fan Feng · Jianyong Zheng · Jian Zhang
Oncogene, Published online: 19 May 2026; doi:10.1038/s41388-026-03823-8NDRG2 orchestrates circadian clock stability to suppress tumorigenesis and potentiate oxaliplatin response in colorectal cancer
19 May 2026 at 08:00

NDRG2 orchestrates circadian clock stability to suppress tumorigenesis and potentiate oxaliplatin response in colorectal cancer

Oncogene - Issue - nature.com science feeds

By: Ruikai Li · Ruxin Ding · Hanjun Dan · Kunli Du · Gaozan Zheng · Siyuan Wang · Lili Duan · Pengfei Wang · Liangliang Shen · Lin Feng · Pan Zhao · Jiajia Wang · Dan Feng · Fengsu Wu · Yumao Yang · Ziting Zhou · Liaoran Niu · Weidong Wang · Xinyu Qiao · Jianting Yang · Fan Feng · Jianyong Zheng · Jian Zhang

19 May 2026 at 08:00

Oncogene, Published online: 19 May 2026; doi:10.1038/s41388-026-03823-8

NDRG2 orchestrates circadian clock stability to suppress tumorigenesis and potentiate oxaliplatin response in colorectal cancer

Oncogene - Issue - nature.com science feeds
ESR1 fusion proteins in breast cancer: distinguishing oncogenic drivers from passenger events Ana-Maria Gherghelas · Christopher P. Toseland
Oncogene, Published online: 14 May 2026; doi:10.1038/s41388-026-03813-wESR1 fusion proteins in breast cancer: distinguishing oncogenic drivers from passenger events
14 May 2026 at 08:00

ESR1 fusion proteins in breast cancer: distinguishing oncogenic drivers from passenger events

Oncogene - Issue - nature.com science feeds

By: Ana-Maria Gherghelas · Christopher P. Toseland

14 May 2026 at 08:00

Oncogene, Published online: 14 May 2026; doi:10.1038/s41388-026-03813-w

ESR1 fusion proteins in breast cancer: distinguishing oncogenic drivers from passenger events

Oncogene - Issue - nature.com science feeds
Editorial Expression of Concern: Disruption of transforming growth factor-β signaling through β-spectrin ELF leads to hepatocellular cancer through cyclin D1 activation K. Kitisin · N. Ganesan · Y. Tang · W. Jogunoori · E. A. Volpe · S. S. Kim · V. Katuri · B. Kallakury · M. Pishvaian · C. Albanese · J. Mendelson · M. Zasloff · A. Rashid · T. Fishbein · S. R. T. Evans · A. Sidawy · E. P. Reddy · B. Mishra · L. B. Johnson · K. Shetty · L. Mishra
Oncogene, Published online: 11 May 2026; doi:10.1038/s41388-026-03821-wEditorial Expression of Concern: Disruption of transforming growth factor-β signaling through β-spectrin ELF leads to hepatocellular cancer through cyclin D1 activation
11 May 2026 at 08:00

Editorial Expression of Concern: Disruption of transforming growth factor-β signaling through β-spectrin ELF leads to hepatocellular cancer through cyclin D1 activation

Oncogene - Issue - nature.com science feeds

By: K. Kitisin · N. Ganesan · Y. Tang · W. Jogunoori · E. A. Volpe · S. S. Kim · V. Katuri · B. Kallakury · M. Pishvaian · C. Albanese · J. Mendelson · M. Zasloff · A. Rashid · T. Fishbein · S. R. T. Evans · A. Sidawy · E. P. Reddy · B. Mishra · L. B. Johnson · K. Shetty · L. Mishra

11 May 2026 at 08:00

Oncogene, Published online: 11 May 2026; doi:10.1038/s41388-026-03821-w

Editorial Expression of Concern: Disruption of transforming growth factor-β signaling through β-spectrin ELF leads to hepatocellular cancer through cyclin D1 activation

Oncogene - Issue - nature.com science feeds
Sirt1 sustains Sonic hedgehog signaling to promote medulloblastoma progression through regulating Gli3 processing Jian Hu · Chaonan Zheng · Yingying Feng · Yuhang Li · Panpan Pei · Man Yang · Yanghui Qu · Long-Tai Zheng · Li Zhang · Xue-Chu Zhen · Yuan Wang
Oncogene, Published online: 18 April 2026; doi:10.1038/s41388-026-03781-1Sirt1 sustains Sonic hedgehog signaling to promote medulloblastoma progression through regulating Gli3 processing
18 April 2026 at 08:00

Sirt1 sustains Sonic hedgehog signaling to promote medulloblastoma progression through regulating Gli3 processing

Oncogene - Issue - nature.com science feeds

By: Jian Hu · Chaonan Zheng · Yingying Feng · Yuhang Li · Panpan Pei · Man Yang · Yanghui Qu · Long-Tai Zheng · Li Zhang · Xue-Chu Zhen · Yuan Wang

18 April 2026 at 08:00

Oncogene, Published online: 18 April 2026; doi:10.1038/s41388-026-03781-1

Sirt1 sustains Sonic hedgehog signaling to promote medulloblastoma progression through regulating Gli3 processing

Oncogene - Issue - nature.com science feeds
iPalmT: a new paradigm for palmitoyltransferase discovery via end-to-end deep learning Tengda Li · Xiang Li
Oncogene, Published online: 18 April 2026; doi:10.1038/s41388-026-03802-ziPalmT: a new paradigm for palmitoyltransferase discovery via end-to-end deep learning
18 April 2026 at 08:00

iPalmT: a new paradigm for palmitoyltransferase discovery via end-to-end deep learning

Oncogene - Issue - nature.com science feeds

By: Tengda Li · Xiang Li

18 April 2026 at 08:00

Oncogene, Published online: 18 April 2026; doi:10.1038/s41388-026-03802-z

iPalmT: a new paradigm for palmitoyltransferase discovery via end-to-end deep learning

Oncogene - Issue - nature.com science feeds
Granzyme B-based CAR-T cells targeting membrane-bound HSP70 suppress solid tumor growth and metastasis Bin Sun · Jing Guo · Dong Yang · Qiancheng Hu · Haiyan Ma · Panwen Tian · Nan Liu · Longbao Lv · Lanzhen Yan · Hao Ding · Maoyong Fu · Hongfeng Gou · Dan Cao · Dan Liu · Peng Shi · Nianyong Chen · Weimin Li · Xudong Zhao
Oncogene, Published online: 18 April 2026; doi:10.1038/s41388-026-03797-7Granzyme B-based CAR-T cells targeting membrane-bound HSP70 suppress solid tumor growth and metastasis
18 April 2026 at 08:00

Granzyme B-based CAR-T cells targeting membrane-bound HSP70 suppress solid tumor growth and metastasis

Oncogene - Issue - nature.com science feeds

By: Bin Sun · Jing Guo · Dong Yang · Qiancheng Hu · Haiyan Ma · Panwen Tian · Nan Liu · Longbao Lv · Lanzhen Yan · Hao Ding · Maoyong Fu · Hongfeng Gou · Dan Cao · Dan Liu · Peng Shi · Nianyong Chen · Weimin Li · Xudong Zhao

18 April 2026 at 08:00

Oncogene, Published online: 18 April 2026; doi:10.1038/s41388-026-03797-7

Granzyme B-based CAR-T cells targeting membrane-bound HSP70 suppress solid tumor growth and metastasis

Oncogene - Issue - nature.com science feeds
Antitumor immunotoxin expression is enhanced by Escherichia coli csrB-promoter activity Seyeon Hong · Sung-Gwon Lee · Dogeun Lee · Jihyeon Kim · Miryoung Song · Daejin Lim
Oncogene, Published online: 17 April 2026; doi:10.1038/s41388-026-03796-8Antitumor immunotoxin expression is enhanced by Escherichia coli csrB-promoter activity
17 April 2026 at 08:00

Antitumor immunotoxin expression is enhanced by Escherichia coli csrB-promoter activity

Oncogene - Issue - nature.com science feeds

By: Seyeon Hong · Sung-Gwon Lee · Dogeun Lee · Jihyeon Kim · Miryoung Song · Daejin Lim

17 April 2026 at 08:00

Oncogene, Published online: 17 April 2026; doi:10.1038/s41388-026-03796-8

Antitumor immunotoxin expression is enhanced by Escherichia coli csrB-promoter activity

Normal view

ITGA5 promotes homologous recombination mediated radioresistance in esophageal squamous cell carcinoma by upregulating RAD51AP1 expression

A step-wise, deterministic and fatal mouse model of myeloid neoplasm with spontaneous acquisition of patient-relevant RTK–RAS mutations

The RNA-binding protein La/SSB is associated with HNSCC progression and TFAP2C/FSCN1-linked transcriptional regulation

The <i>GSEC</i>-encoded polypeptide GESP drives colorectal cancer tumorigenesis via NPM1-c-Myc-mediated repression of NDRG1

Neuromedin U ‘innervation’ reprograms myeloid immunosuppression in neuroendocrine prostate cancer

Frequently amplified SHANK2 promotes esophageal squamous cell carcinoma progression through the DVL/YAP axis

POC1A promotes the proliferation, metastasis and stemness of bladder cancer by stabilizing BMI1 via USP7

DHCR24<sup>+</sup> tumor epithelial cells drive cisplatin resistance in bladder cancer by enhancing cholesterol metabolism to activate lipid raft-associated MAPK signaling

Liver-specific <i>SIRT1</i> knockout-induced hyperglycemia promotes spontaneous lung adenocarcinomas through HSF1-MDM2

Signals from the bone marrow B cell niches shape pre-leukemic fate in a murine model of B cell acute lymphoblastic leukemia

Lactic acid induces dendritic cell pyroptosis through MCT-1 to promote tumor immune evasion

GPX8<sup>+</sup> cancer-associated fibroblast-derived lactate contributes to lenvatinib resistance by facilitating BRPF1 expression through histone H3 lysine 18 lactylation in hepatocellular carcinoma

circPARPBP promotes cancer stemness and chemoresistance in triple-negative breast cancer through recruiting SRCAP complex to activate CCL20 transcription

NDRG2 orchestrates circadian clock stability to suppress tumorigenesis and potentiate oxaliplatin response in colorectal cancer

<i>ESR1</i> fusion proteins in breast cancer: distinguishing oncogenic drivers from passenger events

Editorial Expression of Concern: Disruption of transforming growth factor-<i>β</i> signaling through <i>β</i>-spectrin ELF leads to hepatocellular cancer through cyclin D1 activation

Sirt1 sustains Sonic hedgehog signaling to promote medulloblastoma progression through regulating Gli3 processing

iPalmT: a new paradigm for palmitoyltransferase discovery via end-to-end deep learning

Granzyme B-based CAR-T cells targeting membrane-bound HSP70 suppress solid tumor growth and metastasis

Antitumor immunotoxin expression is enhanced by <i>Escherichia coli csrB</i>-promoter activity