arXiv:2601.01576v1 Announce Type: cross Abstract: Evaluating novelty is critical yet challenging in peer review, as reviewers must assess submissions against a vast, rapidly evolving literature. This report presents OpenNovelty, an LLM-powered agentic system for transparent, evidence-based novelty analysis. The system operates through four phases: (1) extracting the core task and contribution claims to generate retrieval queries; (2) retrieving relevant prior work based on extracted queries via semantic search engine; (3) constructing a hierarchical taxonomy of core-task-related work and performing contribution-level full-text comparisons against each contribution; and (4) synthesizing all analyses into a structured novelty report with explicit citations and evidence snippets. Unlike naive LLM-based approaches, \textsc{OpenNovelty} grounds all assessments in retrieved real papers, ensuring verifiable judgments. We deploy our system on 500+ ICLR 2026 submissions with all reports publicly available on our website, and preliminary analysis suggests it can identify relevant prior work, including closely related papers that authors may overlook. OpenNovelty aims to empower the research community with a scalable tool that promotes fair, consistent, and evidence-backed peer review.

arXiv:2512.06879v1 Announce Type: cross Abstract: Researchers struggle to efficiently locate and manage relevant literature within the exponentially growing body of scientific publications. We present \textsc{WisPaper}, an intelligent academic retrieval and literature management platform that addresses this challenge through three integrated capabilities: (1) \textit{Scholar Search}, featuring both quick keyword-based and deep agentic search modes for efficient paper discovery; (2) \textit{Library}, a customizable knowledge base for systematic literature organization; and (3) \textit{AI Feeds}, an intelligent recommendation system that automatically delivers relevant new publications based on user interests. Unlike existing academic tools, \textsc{WisPaper} provides a closed-loop workflow that seamlessly connects literature discovery, management, and continuous tracking of research frontiers. Our multilingual and multidisciplinary system significantly reduces the time researchers from diverse backgrounds spend on paper screening and management, enabling them to focus on their core research activities. The platform is publicly accessible and serves researchers across academia and industry.

arXiv:2502.07663v3 Announce Type: replace Abstract: AI systems are increasingly intertwined with daily life, assisting users with various tasks and guiding decision-making. This integration introduces risks of AI-driven manipulation, where such systems may exploit users' cognitive biases and emotional vulnerabilities to steer them toward harmful outcomes. Through a randomized between-subjects experiment with 233 participants, we examined human susceptibility to such manipulation in financial (e.g., purchases) and emotional (e.g., conflict resolution) decision-making contexts. Participants interacted with one of three AI agents: a neutral agent (NA) optimizing for user benefit without explicit influence, a manipulative agent (MA) designed to covertly influence beliefs and behaviors, or a strategy-enhanced manipulative agent (SEMA) equipped with established psychological tactics, allowing it to select and apply them adaptively during interactions to reach its hidden objectives. By analyzing participants' preference ratings, we found significant susceptibility to AI-driven manipulation. Particularly across both decision-making domains, interacting with the manipulative agents significantly increased the odds of rating hidden incentives higher than optimal options (Financial, MA: OR=5.24, SEMA: OR=7.96; Emotional, MA: OR=5.52, SEMA: OR=5.71) compared to the NA group. Notably, we found no clear evidence that employing psychological strategies (SEMA) was overall more effective than simple manipulative objectives (MA) on our primary outcomes. Hence, AI-driven manipulation could become widespread even without requiring sophisticated tactics and expertise. While our findings are preliminary and derived from hypothetical, low-stakes scenarios, we highlight a critical vulnerability in human-AI interactions, emphasizing the need for ethical safeguards and regulatory frameworks to protect human autonomy.

arXiv:2502.07299v3 Announce Type: replace-cross Abstract: The interactions between DNA, RNA, and proteins are fundamental to biological processes, as illustrated by the central dogma of molecular biology. Although modern biological pre-trained models have achieved great success in analyzing these macromolecules individually, their interconnected nature remains underexplored. This paper follows the guidance of the central dogma to redesign both the data and model pipeline and offers a comprehensive framework, Life-Code, that spans different biological functions. As for data flow, we propose a unified pipeline to integrate multi-omics data by reverse-transcribing RNA and reverse-translating amino acids into nucleotide-based sequences. As for the model, we design a codon tokenizer and a hybrid long-sequence architecture to encode the interactions between coding and non-coding regions through masked modeling pre-training. To model the translation and folding process with coding sequences, Life-Code learns protein structures of the corresponding amino acids by knowledge distillation from off-the-shelf protein language models. Such designs enable Life-Code to capture complex interactions within genetic sequences, providing a more comprehensive understanding of multi-omics with the central dogma. Extensive experiments show that Life-Code achieves state-of-the-art results on various tasks across three omics, highlighting its potential for advancing multi-omics analysis and interpretation.

arXiv:2511.11587v2 Announce Type: replace-cross Abstract: Globally, disparities in healthcare infrastructure remain stark, leaving countless communities without access to even basic services. Traditional infrastructure planning is often slow and inaccessible, and although many architects are actively delivering humanitarian and aid-driven hospital projects worldwide, these vital efforts still fall far short of the sheer scale and urgency of demand. This paper introduces MedBuild AI, a hybrid-intelligence framework that integrates large language models (LLMs) with deterministic expert systems to rebalance the early design and conceptual planning stages. As a web-based platform, it enables any region with satellite internet access to obtain guidance on modular, low-tech, low-cost medical building designs. The system operates through three agents: the first gathers local health intelligence via conversational interaction; the second translates this input into an architectural functional program through rule-based computation; and the third generates layouts and 3D models. By embedding computational negotiation into the design process, MedBuild AI fosters a reciprocal, inclusive, and equitable approach to healthcare planning, empowering communities and redefining agency in global healthcare architecture.

arXiv:2511.11587v1 Announce Type: cross Abstract: Globally, disparities in healthcare infrastructure remain stark, leaving countless communities without access to even basic services. Traditional infrastructure planning is often slow and inaccessible, and although many architects are actively delivering humanitarian and aid-driven hospital projects worldwide, these vital efforts still fall far short of the sheer scale and urgency of demand. This paper introduces MedBuild AI, a hybrid-intelligence framework that integrates large language models (LLMs) with deterministic expert systems to rebalance the early design and conceptual planning stages. As a web-based platform, it enables any region with satellite internet access to obtain guidance on modular, low-tech, low-cost medical building designs. The system operates through three agents: the first gathers local health intelligence via conversational interaction; the second translates this input into an architectural functional program through rule-based computation; and the third generates layouts and 3D models. By embedding computational negotiation into the design process, MedBuild AI fosters a reciprocal, inclusive, and equitable approach to healthcare planning, empowering communities and redefining agency in global healthcare architecture.

arXiv:2506.20535v2 Announce Type: replace-cross Abstract: The rapid advancement of AI, particularly large language models (LLMs), has raised significant concerns about the energy use and carbon emissions associated with model training and inference. However, existing tools for measuring and reporting such impacts are often fragmented, lacking systematic metric integration and offering limited support for correlation analysis among them. This paper presents AIMeter, a comprehensive software toolkit for the measurement, analysis, and visualization of energy use, power draw, hardware performance, and carbon emissions across AI workloads. By seamlessly integrating with existing AI frameworks, AIMeter offers standardized reports and exports fine-grained time-series data to support benchmarking and reproducibility in a lightweight manner. It further enables in-depth correlation analysis between hardware metrics and model performance and thus facilitates bottleneck identification and performance enhancement. By addressing critical limitations in existing tools, AIMeter encourages the research community to weigh environmental impact alongside raw performance of AI workloads and advances the shift toward more sustainable "Green AI" practices. The code is available at https://github.com/SusCom-Lab/AIMeter.

Oncogene, Published online: 22 September 2023; doi:10.1038/s41388-023-02843-y

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