arXiv:2605.17537v2 Announce Type: replace Abstract: 3D open-world environments with adversarial opponents remain a core challenge for reinforcement learning due to their vast state spaces. Effective reasoning representations are essential in such settings. While existing self-supervised visual foresight reasoning approaches often suffer from multi-step error accumulation, many recent studies resort to injecting domain-specific knowledge for more stable guidance. Our key insight is that the photorealistic fidelity of visual reasoning representations is secondary; what truly matters is providing informative, task-relevant signals. To this end, we propose ResDreamer, a hierarchical world model in which each higher-level layer is trained to reconstruct the residuals of the layer below. This design enables progressive abstraction of increasingly sophisticated world dynamics and fosters the emergence of richer latent representations. Drawing inspiration from the "Bitter Lesson", ResDreamer trains its reasoning representations in a purely self-supervised manner. The higher-level residual representations are used to modulate lower-level predictions, allowing the world model to scale effectively with only linearly increasing cross-layer communication costs. Experiments show that ResDreamer achieves state-of-the-art sample efficiency and parameter efficiency. This scalable hierarchical visual foresight reasoning architecture paves the way for more capable online RL agents in open-ended, dynamic environments. The code is accessible at https://github.com/XuYuanFei01/ResDreamer.

Oncogene, Published online: 07 April 2026; doi:10.1038/s41388-026-03753-5

PIAS4 inhibition induces cell cycle arrest and exhibits a synergistic effect in combination with CDK4/6 inhibitor in breast cancer treatment

arXiv:2603.28458v3 Announce Type: replace-cross Abstract: Token-level sparse attention mechanisms, exemplified by DeepSeek Sparse Attention (DSA), achieve fine-grained key selection by scoring every historical key for each query through a lightweight indexer, then computing attention only on the selected subset. While the downstream sparse attention itself scales favorably, the indexer must still scan the entire prefix for every query, introducing an per-layer bottleneck that grows prohibitively with context length. We propose HISA (Hierarchical Indexed Sparse Attention), a plug-and-play replacement for the indexer that rewrites the search path from a flat token scan into a two-stage hierarchical procedure: (1) a block-level coarse filtering stage that scores pooled block representations to discard irrelevant regions, followed by (2) a token-level refinement stage that applies the original indexer exclusively within the retained candidate blocks. HISA preserves the identical token-level top-sparse pattern consumed by the downstream Sparse MLA operator and requires no additional training. On kernel-level benchmarks, HISA achieves up to speedup at 64K context. On Needle-in-a-Haystack and LongBench, we directly replace the indexer in DeepSeek-V3.2 and GLM-5 with our HISA indexer, without any finetuning. HISA closely matches the original DSA in quality, while substantially outperforming block-sparse baselines.

Nature, Published online: 10 March 2026; doi:10.1038/s41586-026-10351-8

Maximizing carrier extraction in hybrid back-contact silicon solar cells

arXiv:2603.00376v2 Announce Type: replace Abstract: NeuroHex is a hexagonal coordinate system designed to support highly efficient world models and reference frames for online adaptive AI systems. Inspired by the hexadirectional firing structure of grid cells in the human brain, NeuroHex adopts a cubic isometric hexagonal coordinate formulation that provides full 60{\deg} rotational symmetry and low-cost translation, rotation and distance computation. We develop a mathematical framework that incorporates ring indexing, quantized angular encoding, and a hierarchical library of foundational, simple, and complex geometric shape primitives. These constructs allow low-overhead point-in-shape tests and spatial matching operations that are expensive in Cartesian coordinate systems. To support realistic settings, the NeuroHex framework can process OpenStreetMap (OSM) data sets using an OSM-to-NeuroHex (OSM2Hex) conversion tool. The OSM2Hex spatial abstraction processing pipeline can achieve a reduction of 90-99% in geometric complexity while maintaining the relevant spatial structure map for navigation. Our initial results, based on actual city and neighborhood scale data sets, demonstrate that NeuroHex offers a highly efficient substrate for building dynamic world models to enable adaptive spatial reasoning in autonomous AI systems with continuous online learning capability.