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Reinforcement Learning with Temporal-Logic-Based Causal Diagrams

arXiv:2306.13732v2 Announce Type: replace Abstract: We study a class of reinforcement learning (RL) tasks where the objective of the agent is to accomplish temporally extended goals. In this setting, a common approach is to represent the tasks as deterministic finite automata (DFA) and integrate them into the state-space for RL algorithms. However, while these machines model the reward function, they often overlook the causal knowledge about the environment. To address this limitation, we propose the Temporal-Logic-based Causal Diagram (TL-CD) in RL, which captures the temporal causal relationships between different properties of the environment. We exploit the TL-CD to devise an RL algorithm in which an agent requires significantly less exploration of the environment. To this end, based on a TL-CD and a task DFA, we identify configurations where the agent can determine the expected rewards early during an exploration. Through a series of case studies, we demonstrate the benefits of using TL-CDs, particularly the faster convergence of the algorithm to an optimal policy due to reduced exploration of the environment.

TGFormer: Towards Temporal Graph Transformer with Auto-Correlation Mechanism

arXiv:2605.24971v1 Announce Type: cross Abstract: The growing interest in Temporal Graph Neural Networks (TGNNs) stems from their ability to model complex dynamics and deliver superior performance. However, TGNNs encounter fundamental challenges in capturing long-term dependencies and identifying periodic patterns. To address these limitations, we propose TGFormer, a novel Transformer architecture specifically designed for temporal graphs. Our model redefines temporal graph learning by establishing a trajectory framework that aligns with time series analysis principles. This approach allows TGFormer to derive node representations through systematic analysis of historical interactions, enabling granular examination of node relationships across sequential timestamps. Building upon stochastic process theory, we develop an auto-correlation mechanism that systematically uncovers periodic dependencies in node interactions. This innovation empowers TGFormer to perform dependency discovery and representation aggregation at sub-interaction levels, demonstrating superior efficiency and accuracy compared to conventional attention mechanisms. Experimental validation across six public benchmarks confirms the effectiveness of our approach, with TGFormer at most achieving 9.35\% precision improvement compared to state-of-the-art approaches.

CVEvolve: Autonomous Algorithm Discovery for Unstructured Scientific Data Processing

arXiv:2605.11359v2 Announce Type: replace Abstract: Scientific data processing often requires task-specific algorithms or AI models, creating a barrier for domain scientists who need to analyze their data but may not have extensive computing or image-processing expertise. This barrier is especially pronounced when data are noisy, have a high dynamic range, are sparsely labeled, or are only loosely specified. We introduce CVEvolve, an autonomous agentic harness with a zero-code interface for scientific data-processing algorithm discovery. CVEvolve combines a multi-round search strategy with tools for code execution, evaluation implementation, history management, holdout testing, and optional inspection of scientific data and visual outputs. The search alternates between discovery and improvement actions, and uses lineage-aware stochastic candidate sampling to balance exploration and exploitation. We demonstrate CVEvolve on x-ray fluorescence microscopy image registration, Bragg peak detection, and high-energy diffraction microscopy image segmentation. Across these tasks, CVEvolve discovers algorithms that improve over baseline methods, while holdout test tracking helps identify candidates that generalize better than later over-optimized alternatives. These results show that zero-code, autonomous LLM-powered algorithm development can help domain scientists turn unstructured scientific image data into practical algorithms and downstream scientific discoveries.

Risk-adaptive therapy guided by dynamic ctDNA in nasopharyngeal carcinoma

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10244-w

A clinical trial testing whether monitoring ctDNA clearance during treatment for nasopharyngeal cancer could be used to inform decisions about an individual’s subsequent therapeutic programme shows promising results.
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