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cs.AI, q-bio.NC updates on arXiv.org
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Hera: Learning Long-Horizon Coordination for Device-Cloud Collaborative LLM Agents
arXiv:2605.24598v1 Announce Type: new Abstract: Large language model (LLM) agents excel at solving complex long-horizon tasks through autonomous interaction with environments. However, their real-world deployment faces a fundamental device--cloud dilemma: on-device models are efficient but often brittle, while cloud models are stronger but costly in computation. State-of-the-art LLM device--cloud routers usually make coarse task-level decisions, which cannot adapt to the changing difficulty of
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(Multiomics OR Omics) AND (Lung OR gastric OR Hepatocellular)
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Spatial Omics in Gastrointestinal Oncology: Recent Advances, Therapeutic Insights, and Clinical Translation
J Cancer. 2026 Jan 30;17(3):515-523. doi: 10.7150/jca.127381. eCollection 2026.ABSTRACTGastrointestinal (GI) cancers remain a leading cause of cancer-related morbidity and mortality worldwide, largely due to their molecular heterogeneity, complex tumor microenvironment (TME), and variable treatment responses. In recent years, the emergence of spatially resolved omics technologies-encompassing spatial transcriptomics, proteomics, metabolomics, and epigenomics-has revolutionized the ability to int
Spatial Omics in Gastrointestinal Oncology: Recent Advances, Therapeutic Insights, and Clinical Translation
J Cancer. 2026 Jan 30;17(3):515-523. doi: 10.7150/jca.127381. eCollection 2026.
ABSTRACT
Gastrointestinal (GI) cancers remain a leading cause of cancer-related morbidity and mortality worldwide, largely due to their molecular heterogeneity, complex tumor microenvironment (TME), and variable treatment responses. In recent years, the emergence of spatially resolved omics technologies-encompassing spatial transcriptomics, proteomics, metabolomics, and epigenomics-has revolutionized the ability to interrogate tumor architecture with unprecedented resolution. These methods enable precise mapping of cellular and molecular interactions within intact tissue contexts, thereby uncovering spatially defined niches that influence tumor progression, immune evasion, and therapeutic resistance. In GI malignancies such as colorectal, gastric, and esophageal cancers, spatial omics have provided critical insights into cancer-stromal-immune crosstalk, identified predictive biomarkers for immunotherapy and targeted agents, and guided the development of novel therapeutic strategies. This review synthesizes the latest advances in spatial omics applied to GI oncology over the past five years, with an emphasis on their integration into early diagnosis, treatment stratification, and real-time monitoring of therapeutic efficacy. We also discuss current challenges, including standardization, data integration, and clinical validation, as well as future directions for incorporating spatial profiling into routine oncology practice. By bridging the gap between bench discoveries and bedside applications, spatial omics hold transformative potential for achieving truly personalized treatment in gastrointestinal cancers.
PMID:41869445 | PMC:PMC13003551 | DOI:10.7150/jca.127381
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cs.AI, q-bio.NC updates on arXiv.org
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MEBM-Phoneme: Multi-scale Enhanced BrainMagic for End-to-End MEG Phoneme Classification
arXiv:2603.02254v1 Announce Type: cross Abstract: We propose MEBM-Phoneme, a multi-scale enhanced neural decoder for phoneme classification from non-invasive magnetoencephalography (MEG) signals. Built upon the BrainMagic backbone, MEBM-Phoneme integrates a short-term multi-scale convolutional module to augment the native mid-term encoder, with fused representations via depthwise separable convolution for efficient cross-scale integration. A convolutional attention layer dynamically weights tem
MEBM-Phoneme: Multi-scale Enhanced BrainMagic for End-to-End MEG Phoneme Classification
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cs.AI, q-bio.NC updates on arXiv.org
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MEBM-Speech: Multi-scale Enhanced BrainMagic for Robust MEG Speech Detection
arXiv:2603.02255v1 Announce Type: cross Abstract: We propose MEBM-Speech, a multi-scale enhanced neural decoder for speech activity detection from non-invasive magnetoencephalography (MEG) signals. Built upon the BrainMagic backbone, MEBM-Speech integrates three complementary temporal modeling mechanisms: a multi-scale convolutional module for short-term pattern extraction, a bidirectional LSTM (BiLSTM) for long-range context modeling, and a depthwise separable convolutional layer for efficient