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Biomolecular profiling for noninvasive health monitoring

Nature Biotechnology, Published online: 12 March 2026; doi:10.1038/s41587-026-03050-2

Kim et al. present mass spectrometry and wearable sensor technology as complementary approaches that, when integrated, can co-evolve to open new possibilities for noninvasive health monitoring.

CMI-RewardBench: Evaluating Music Reward Models with Compositional Multimodal Instruction

arXiv:2603.00610v2 Announce Type: replace-cross Abstract: While music generation models have evolved to handle complex multimodal inputs mixing text, lyrics, and reference audio, evaluation mechanisms have lagged behind. In this paper, we bridge this critical gap by establishing a comprehensive ecosystem for music reward modeling under Compositional Multimodal Instruction (CMI), where the generated music may be conditioned on text descriptions, lyrics, and audio prompts. We first introduce CMI-Pref-Pseudo, a large-scale preference dataset comprising 110k pseudo-labeled samples, and CMI-Pref, a high-quality, human-annotated corpus tailored for fine-grained alignment tasks. To unify the evaluation landscape, we propose CMI-RewardBench, a unified benchmark that evaluates music reward models on heterogeneous samples across musicality, text-music alignment, and compositional instruction alignment. Leveraging these resources, we develop CMI reward models (CMI-RMs), a parameter-efficient reward model family capable of processing heterogeneous inputs. We evaluate their correlation with human judgments scores on musicality and alignment on CMI-Pref along with previous datasets. Further experiments demonstrate that CMI-RM not only correlates strongly with human judgments, but also enables effective inference-time scaling via top-k filtering. The necessary training data, benchmarks, and reward models are publicly available.

Whom to Query for What: Adaptive Group Elicitation via Multi-Turn LLM Interactions

arXiv:2602.14279v1 Announce Type: cross Abstract: Eliciting information to reduce uncertainty about latent group-level properties from surveys and other collective assessments requires allocating limited questioning effort under real costs and missing data. Although large language models enable adaptive, multi-turn interactions in natural language, most existing elicitation methods optimize what to ask with a fixed respondent pool, and do not adapt respondent selection or leverage population structure when responses are partial or incomplete. To address this gap, we study adaptive group elicitation, a multi-round setting where an agent adaptively selects both questions and respondents under explicit query and participation budgets. We propose a theoretically grounded framework that combines (i) an LLM-based expected information gain objective for scoring candidate questions with (ii) heterogeneous graph neural network propagation that aggregates observed responses and participant attributes to impute missing responses and guide per-round respondent selection. This closed-loop procedure queries a small, informative subset of individuals while inferring population-level responses via structured similarity. Across three real-world opinion datasets, our method consistently improves population-level response prediction under constrained budgets, including a >12% relative gain on CES at a 10% respondent budget.
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