Normal view
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cs.AI, q-bio.NC updates on arXiv.org
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SARE: Sample-wise Adaptive Reasoning for Training-free Fine-grained Visual Recognition
arXiv:2603.17729v2 Announce Type: replace-cross Abstract: Recent advances in Large Vision-Language Models (LVLMs) have enabled training-free Fine-Grained Visual Recognition (FGVR). However, effectively exploiting LVLMs for FGVR remains challenging due to the inherent visual ambiguity of subordinate-level categories. Existing methods predominantly adopt either retrieval-oriented or reasoning-oriented paradigms to tackle this challenge, but both are constrained by two fundamental limitations:(1)
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Pulmonary nodule
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A Review of the Role of Zeqi Decoction in the Treatment of Non-Small Cell Lung Cancer
J Multidiscip Healthc. 2026 Mar 11;19:584071. doi: 10.2147/JMDH.S584071. eCollection 2026.ABSTRACTNon-small cell lung cancer (NSCLC) is one of the malignant tumors with the highest incidence and mortality rates. Zeqi Decoction has the functions of "promoting diuresis and reducing swelling, resolving phlegm and dispersing nodules", embodying the unique approach of traditional Chinese medicine in treating lung cancer by "strengthening the body's resistance and eliminating pathogenic factors". Mode
A Review of the Role of Zeqi Decoction in the Treatment of Non-Small Cell Lung Cancer
J Multidiscip Healthc. 2026 Mar 11;19:584071. doi: 10.2147/JMDH.S584071. eCollection 2026.
ABSTRACT
Non-small cell lung cancer (NSCLC) is one of the malignant tumors with the highest incidence and mortality rates. Zeqi Decoction has the functions of "promoting diuresis and reducing swelling, resolving phlegm and dispersing nodules", embodying the unique approach of traditional Chinese medicine in treating lung cancer by "strengthening the body's resistance and eliminating pathogenic factors". Modern research shows that Zeqi Decoction exerts anti-NSCLC effects through multiple pathways and targets. In terms of the material basis of its efficacy, its active ingredients (such as diterpene esters and flavonoids contained in Zeqi) have the ability to directly inhibit the proliferation, invasion and migration of tumor cells and induce apoptosis. In terms of the mechanism of action, basic experiments have revealed that Zeqi Decoction can down-regulate the S100A9/STAT3 signaling pathway, inhibit the immunosuppressive activity of myelium-derived suppressor cells (MDSCs), reshape the tumor microenvironment, thereby enhancing the cytotoxic function of CD8⁺T cells, and can also regulate the EGFR/PI3K/Akt pathway to affect PD-L1 expression. Intervene in tumor immune escape; In terms of clinical transformation, the combination of Zexi Decoction with chemotherapy and targeted therapy can improve patients' symptoms such as cough and pleural effusion, prolong progression-free survival, and alleviate the toxic and side effects of Western medical treatment. In addition, Zexi Decoction also shows potential value in reversing drug resistance such as gemcitabine. At present, there are still problems such as the lack of standardized protocols and unclear molecular mechanisms in the research. In the future, it is necessary to combine new technologies such as network pharmacology and multi-omics analysis to deepen the research on the pharmacological material basis, dose-effect relationship and evidence-based medicine of Zeqi Decoction, so as to promote the clinical application and transformation of the combination of traditional Chinese and Western medicine in the treatment of NSCLC.
PMID:41847115 | PMC:PMC12991379 | DOI:10.2147/JMDH.S584071
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cs.AI, q-bio.NC updates on arXiv.org
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FedBPrompt: Federated Domain Generalization Person Re-Identification via Body Distribution Aware Visual Prompts
arXiv:2603.12912v1 Announce Type: cross Abstract: Federated Domain Generalization for Person Re-Identification (FedDG-ReID) learns domain-invariant representations from decentralized data. While Vision Transformer (ViT) is widely adopted, its global attention often fails to distinguish pedestrians from high similarity backgrounds or diverse viewpoints -- a challenge amplified by cross-client distribution shifts in FedDG-ReID. To address this, we propose Federated Body Distribution Aware Visual
FedBPrompt: Federated Domain Generalization Person Re-Identification via Body Distribution Aware Visual Prompts
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cs.AI, q-bio.NC updates on arXiv.org
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GeoChemAD: Benchmarking Unsupervised Geochemical Anomaly Detection for Mineral Exploration
arXiv:2603.13068v1 Announce Type: cross Abstract: Geochemical anomaly detection plays a critical role in mineral exploration as deviations from regional geochemical baselines may indicate mineralization. Existing studies suffer from two key limitations: (1) single region scenarios which limit model generalizability; (2) proprietary datasets, which makes result reproduction unattainable. In this work, we introduce \textbf{GeoChemAD}, an open-source benchmark dataset compiled from government-led
GeoChemAD: Benchmarking Unsupervised Geochemical Anomaly Detection for Mineral Exploration
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cs.AI, q-bio.NC updates on arXiv.org
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OpenSage: Self-programming Agent Generation Engine
arXiv:2602.16891v2 Announce Type: replace Abstract: Agent development kits (ADKs) provide effective platforms and tooling for constructing agents, and their designs are critical to the constructed agents' performance, especially the functionality for agent topology, tools, and memory. However, current ADKs either lack sufficient functional support or rely on humans to manually design these components, limiting agents' generalizability and overall performance. We propose OpenSage, the first ADK
OpenSage: Self-programming Agent Generation Engine
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cs.AI, q-bio.NC updates on arXiv.org
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Superficial Safety Alignment Hypothesis
arXiv:2410.10862v3 Announce Type: replace-cross Abstract: As large language models (LLMs) are overwhelmingly more and more integrated into various applications, ensuring they generate safe responses is a pressing need. Previous studies on alignment have largely focused on general instruction-following but have often overlooked the distinct properties of safety alignment, such as the brittleness of safety mechanisms. To bridge the gap, we propose the Superficial Safety Alignment Hypothesis (SSAH
Superficial Safety Alignment Hypothesis
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cs.AI, q-bio.NC updates on arXiv.org
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LatentChem: From Textual CoT to Latent Thinking in Chemical Reasoning
arXiv:2602.07075v4 Announce Type: replace-cross Abstract: Chemical large language models (LLMs) predominantly rely on explicit Chain-of-Thought (CoT) in natural language to perform complex reasoning. However, chemical reasoning is inherently continuous and structural, and forcing it into discrete linguistic tokens introduces a fundamental representation mismatch that constrains both efficiency and performance. We introduce LatentChem, a latent reasoning interface that decouples chemical computa
LatentChem: From Textual CoT to Latent Thinking in Chemical Reasoning
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Nature - Issue - nature.com science feeds
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Author Correction: Gut stem cell necroptosis by genome instability triggers bowel inflammation
Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10302-3Author Correction: Gut stem cell necroptosis by genome instability triggers bowel inflammation
Author Correction: Gut stem cell necroptosis by genome instability triggers bowel inflammation
Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10302-3
Author Correction: Gut stem cell necroptosis by genome instability triggers bowel inflammation-
Nature Biotechnology - Issue - nature.com science feeds
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Quantifying endosomal escape in vivo to guide lipid nanoparticle design
Nature Biotechnology, Published online: 11 March 2026; doi:10.1038/s41587-026-03047-xA lysosomal barcoding strategy to quantify endosomal escape of nucleic acids in vivo assesses the performance of branched ionizable lipids for potent liver delivery.
Quantifying endosomal escape in vivo to guide lipid nanoparticle design
Nature Biotechnology, Published online: 11 March 2026; doi:10.1038/s41587-026-03047-x
A lysosomal barcoding strategy to quantify endosomal escape of nucleic acids in vivo assesses the performance of branched ionizable lipids for potent liver delivery.-
cs.AI, q-bio.NC updates on arXiv.org
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CDRRM: Contrast-Driven Rubric Generation for Reliable and Interpretable Reward Modeling
arXiv:2603.08035v1 Announce Type: new Abstract: Reward modeling is essential for aligning Large Language Models(LLMs) with human preferences, yet conventional reward models suffer from poor interpretability and heavy reliance on costly expert annotations. While recent rubric-based approaches enhance evaluation transparency, they lack systematic quality control, yielding noisy and redundant criteria, failing to mitigate persistent biases (e.g., verbosity, position) in LLM evaluators, and creatin
CDRRM: Contrast-Driven Rubric Generation for Reliable and Interpretable Reward Modeling
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cs.AI, q-bio.NC updates on arXiv.org
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Thinking with Gaze: Sequential Eye-Tracking as Visual Reasoning Supervision for Medical VLMs
arXiv:2603.06697v1 Announce Type: cross Abstract: Vision--language models (VLMs) process images as visual tokens, yet their intermediate reasoning is often carried out in text, which can be suboptimal for visually grounded radiology tasks. Radiologists instead diagnose via sequential visual search; eye-tracking captures this process as time-ordered gaze trajectories that reveal how evidence is acquired over time. We use eye-gaze as supervision to guide VLM reasoning by introducing a small set o
Thinking with Gaze: Sequential Eye-Tracking as Visual Reasoning Supervision for Medical VLMs
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cs.AI, q-bio.NC updates on arXiv.org
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Sparsity and Out-of-Distribution Generalization
arXiv:2603.07388v1 Announce Type: cross Abstract: Explaining out-of-distribution generalization has been a central problem in epistemology since Goodman's "grue" puzzle in 1946. Today it's a central problem in machine learning, including AI alignment. Here we propose a principled account of OOD generalization with three main ingredients. First, the world is always presented to experience not as an amorphous mass, but via distinguished features (for example, visual and auditory channels). Seco
Sparsity and Out-of-Distribution Generalization
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cs.AI, q-bio.NC updates on arXiv.org
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FreeKV: Boosting KV Cache Retrieval for Efficient LLM Inference
arXiv:2505.13109v5 Announce Type: replace-cross Abstract: Large language models (LLMs) are widely deployed with rapidly expanding context windows to support increasingly demanding applications. However, long contexts pose significant deployment challenges, primarily due to the KV cache whose size grows proportionally with context length. While KV cache compression methods have been proposed to address this issue, KV dropping methods incur considerable accuracy loss, and KV retrieval methods suf
FreeKV: Boosting KV Cache Retrieval for Efficient LLM Inference
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cs.AI, q-bio.NC updates on arXiv.org
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LifeBench: A Benchmark for Long-Horizon Multi-Source Memory
arXiv:2603.03781v1 Announce Type: new Abstract: Long-term memory is fundamental for personalized agents capable of accumulating knowledge, reasoning over user experiences, and adapting across time. However, existing memory benchmarks primarily target declarative memory, specifically semantic and episodic types, where all information is explicitly presented in dialogues. In contrast, real-world actions are also governed by non-declarative memory, including habitual and procedural types, and need
LifeBench: A Benchmark for Long-Horizon Multi-Source Memory
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cs.AI, q-bio.NC updates on arXiv.org
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DisenReason: Behavior Disentanglement and Latent Reasoning for Shared-Account Sequential Recommendation
arXiv:2603.03782v1 Announce Type: cross Abstract: Shared-account usage is common on streaming and e-commerce platforms, where multiple users share one account. Existing shared-account sequential recommendation (SSR) methods often assume a fixed number of latent users per account, limiting their ability to adapt to diverse sharing patterns and reducing recommendation accuracy. Recent latent reasoning technique applied in sequential recommendation (SR) generate intermediate embeddings from the us
DisenReason: Behavior Disentanglement and Latent Reasoning for Shared-Account Sequential Recommendation
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cs.AI, q-bio.NC updates on arXiv.org
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Preference Leakage: A Contamination Problem in LLM-as-a-judge
arXiv:2502.01534v3 Announce Type: replace-cross Abstract: Large Language Models (LLMs) as judges and LLM-based data synthesis have emerged as two fundamental LLM-driven data annotation methods in model development. While their combination significantly enhances the efficiency of model training and evaluation, little attention has been given to the potential contamination brought by this new model development paradigm. In this work, we expose preference leakage, a contamination problem in LLM-as
Preference Leakage: A Contamination Problem in LLM-as-a-judge
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cs.AI, q-bio.NC updates on arXiv.org
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RxnNano:Training Compact LLMs for Chemical Reaction and Retrosynthesis Prediction via Hierarchical Curriculum Learning
arXiv:2603.02215v1 Announce Type: cross Abstract: Chemical reaction prediction is pivotal for accelerating drug discovery and synthesis planning. Despite advances in data-driven models, current approaches are hindered by an overemphasis on parameter and dataset scaling. Some methods coupled with evaluation techniques that bypass fundamental challenges in reaction representation and fail to capture deep chemical intuition like reaction common sense and {topological atom mapping logic}. We argue
RxnNano:Training Compact LLMs for Chemical Reaction and Retrosynthesis Prediction via Hierarchical Curriculum Learning
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cs.AI, q-bio.NC updates on arXiv.org
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Self-Play Only Evolves When Self-Synthetic Pipeline Ensures Learnable Information Gain
arXiv:2603.02218v1 Announce Type: cross Abstract: Large language models (LLMs) make it plausible to build systems that improve through self-evolving loops, but many existing proposals are better understood as self-play and often plateau quickly. A central failure mode is that the loop synthesises more data without increasing learnable information for the next iteration. Through experiments on a self-play coding task, we reveal that sustainable self-evolution requires a self-synthesised data pip
Self-Play Only Evolves When Self-Synthetic Pipeline Ensures Learnable Information Gain
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cs.AI, q-bio.NC updates on arXiv.org
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UniG2U-Bench: Do Unified Models Advance Multimodal Understanding?
arXiv:2603.03241v1 Announce Type: cross Abstract: Unified multimodal models have recently demonstrated strong generative capabilities, yet whether and when generation improves understanding remains unclear. Existing benchmarks lack a systematic exploration of the specific tasks where generation facilitates understanding. To this end, we introduce UniG2U-Bench, a comprehensive benchmark categorizing generation-to-understanding (G2U) evaluation into 7 regimes and 30 subtasks, requiring varying de
UniG2U-Bench: Do Unified Models Advance Multimodal Understanding?
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cs.AI, q-bio.NC updates on arXiv.org
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xLLM Technical Report
arXiv:2510.14686v2 Announce Type: replace-cross Abstract: We introduce xLLM, an intelligent and efficient Large Language Model (LLM) inference framework designed for high-performance, large-scale enterprise-grade serving, with deep optimizations for diverse AI accelerators. To address these challenges, xLLM builds a novel decoupled service-engine architecture. At the service layer, xLLM-Service features an intelligent scheduling module that efficiently processes multimodal requests and co-locat