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cs.AI, q-bio.NC updates on arXiv.org
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GUARD-SLM: Token Activation-Based Defense Against Jailbreak Attacks for Small Language Models
arXiv:2603.28817v1 Announce Type: cross Abstract: Small Language Models (SLMs) are emerging as efficient and economically viable alternatives to Large Language Models (LLMs), offering competitive performance with significantly lower computational costs and latency. These advantages make SLMs suitable for resource-constrained and efficient deployment on edge devices. However, existing jailbreak defenses show limited robustness against heterogeneous attacks, largely due to an incomplete understan
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cs.AI, q-bio.NC updates on arXiv.org
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MemRerank: Preference Memory for Personalized Product Reranking
arXiv:2603.29247v1 Announce Type: cross Abstract: LLM-based shopping agents increasingly rely on long purchase histories and multi-turn interactions for personalization, yet naively appending raw history to prompts is often ineffective due to noise, length, and relevance mismatch. We propose MemRerank, a preference memory framework that distills user purchase history into concise, query-independent signals for personalized product reranking. To study this problem, we build an end-to-end benchma
MemRerank: Preference Memory for Personalized Product Reranking
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cs.AI, q-bio.NC updates on arXiv.org
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Scaling the Long Video Understanding of Multimodal Large Language Models via Visual Memory Mechanism
arXiv:2603.29252v1 Announce Type: cross Abstract: Long video understanding is a key challenge that plagues the advancement of \emph{Multimodal Large language Models} (MLLMs). In this paper, we study this problem from the perspective of visual memory mechanism, and proposed a novel and training-free approach, termed \emph{Flexible Memory} (\textbf{FlexMem}). In principle, FlexMem aims to mimic human behavior of video watching, \emph{i.e.}, continually watching video content and recalling the mos
Scaling the Long Video Understanding of Multimodal Large Language Models via Visual Memory Mechanism
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cs.AI, q-bio.NC updates on arXiv.org
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IMPASTO: Integrating Model-Based Planning with Learned Dynamics Models for Robotic Oil Painting Reproduction
arXiv:2603.29315v1 Announce Type: cross Abstract: Robotic reproduction of oil paintings using soft brushes and pigments requires force-sensitive control of deformable tools, prediction of brushstroke effects, and multi-step stroke planning, often without human step-by-step demonstrations or faithful simulators. Given only a sequence of target oil painting images, can a robot infer and execute the stroke trajectories, forces, and colors needed to reproduce it? We present IMPASTO, a robotic oil-p
IMPASTO: Integrating Model-Based Planning with Learned Dynamics Models for Robotic Oil Painting Reproduction
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cs.AI, q-bio.NC updates on arXiv.org
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KEditVis: A Visual Analytics System for Knowledge Editing of Large Language Models
arXiv:2603.29689v1 Announce Type: cross Abstract: Large Language Models (LLMs) demonstrate exceptional capabilities in factual question answering, yet they sometimes provide incorrect responses. To address this issue, knowledge editing techniques have emerged as effective methods for correcting factual information in LLMs. However, typical knowledge editing workflows struggle with identifying the optimal set of model layers for editing and rely on summary indicators that provide insufficient gu
KEditVis: A Visual Analytics System for Knowledge Editing of Large Language Models
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cs.AI, q-bio.NC updates on arXiv.org
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MindCube: Spatial Mental Modeling from Limited Views
arXiv:2506.21458v2 Announce Type: replace Abstract: Can Vision-Language Models (VLMs) imagine the full scene from just a few views, like humans do? Humans form spatial mental models naturally, internal representations of unseen space, to reason about layout, perspective, and motion. Our MindCube benchmark with 21,154 questions across 3,268 images exposes this critical gap, where existing VLMs exhibit near-random performance. Using MindCube, we systematically evaluate how well VLMs build robust
MindCube: Spatial Mental Modeling from Limited Views
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cs.AI, q-bio.NC updates on arXiv.org
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From Efficiency to Adaptivity: A Deeper Look at Adaptive Reasoning in Large Language Models
arXiv:2511.10788v3 Announce Type: replace Abstract: Recent advances in large language models (LLMs) have made reasoning a central benchmark for evaluating intelligence. While prior surveys focus on efficiency by examining how to shorten reasoning chains or reduce computation, this view overlooks a fundamental challenge: current LLMs apply uniform reasoning strategies regardless of task complexity, generating long traces for trivial problems while failing to extend reasoning for difficult tasks.
From Efficiency to Adaptivity: A Deeper Look at Adaptive Reasoning in Large Language Models
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cs.AI, q-bio.NC updates on arXiv.org
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Med-CMR: A Fine-Grained Benchmark Integrating Visual Evidence and Clinical Logic for Medical Complex Multimodal Reasoning
arXiv:2512.00818v2 Announce Type: replace Abstract: MLLMs MLLMs are beginning to appear in clinical workflows, but their ability to perform complex medical reasoning remains unclear. We present Med-CMR, a fine-grained Medical Complex Multimodal Reasoning benchmark. Med-CMR distinguishes from existing counterparts by three core features: 1) Systematic capability decomposition, splitting medical multimodal reasoning into fine-grained visual understanding and multi-step reasoning to enable targete
Med-CMR: A Fine-Grained Benchmark Integrating Visual Evidence and Clinical Logic for Medical Complex Multimodal Reasoning
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cs.AI, q-bio.NC updates on arXiv.org
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Streaming 4D Visual Geometry Transformer
arXiv:2507.11539v2 Announce Type: replace-cross Abstract: Perceiving and reconstructing 3D geometry from videos is a fundamental yet challenging computer vision task. To facilitate interactive and low-latency applications, we propose a streaming visual geometry transformer that shares a similar philosophy with autoregressive large language models. We explore a simple and efficient design and employ a causal transformer architecture to process the input sequence in an online manner. We use tempo
Streaming 4D Visual Geometry Transformer
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cs.AI, q-bio.NC updates on arXiv.org
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QuestA: Expanding Reasoning Capacity in LLMs via Question Augmentation
arXiv:2507.13266v4 Announce Type: replace-cross Abstract: Reinforcement learning (RL) has emerged as a central paradigm for training large language models (LLMs) in reasoning tasks. Yet recent studies question RL's ability to incentivize reasoning capacity beyond the base model. This raises a key challenge: how can RL be adapted to solve harder reasoning problems more effectively? To address this challenge, we propose a simple yet effective strategy via Question Augmentation: introduce partial
QuestA: Expanding Reasoning Capacity in LLMs via Question Augmentation
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cs.AI, q-bio.NC updates on arXiv.org
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AgentDrift: Unsafe Recommendation Drift Under Tool Corruption Hidden by Ranking Metrics in LLM Agents
arXiv:2603.12564v5 Announce Type: replace-cross Abstract: Tool-augmented LLM agents increasingly operate as multi-turn advisors in high-stakes domains, yet their evaluation relies on ranking metrics that measure what is recommended but not whether it is safe for the user. We present a paired-trajectory protocol that replays real financial dialogues under clean and contaminated tool-output conditions across eight LLMs (7B to frontier), decomposing divergence into information-channel and memory-c
AgentDrift: Unsafe Recommendation Drift Under Tool Corruption Hidden by Ranking Metrics in LLM Agents
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cs.AI, q-bio.NC updates on arXiv.org
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InCoder-32B: Code Foundation Model for Industrial Scenarios
arXiv:2603.16790v3 Announce Type: replace-cross Abstract: Recent code large language models have achieved remarkable progress on general programming tasks. Nevertheless, their performance degrades significantly in industrial scenarios that require reasoning about hardware semantics, specialized language constructs, and strict resource constraints. To address these challenges, we introduce InCoder-32B (Industrial-Coder-32B), the first 32B-parameter code foundation model unifying code intelligenc
InCoder-32B: Code Foundation Model for Industrial Scenarios
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cs.AI, q-bio.NC updates on arXiv.org
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LLMON: An LLM-native Markup Language to Leverage Structure and Semantics at the LLM Interface
arXiv:2603.22519v2 Announce Type: replace-cross Abstract: Textual Large Language Models (LLMs) provide a simple and familiar interface: a string of text is used for both input and output. However, the information conveyed to an LLM often has a richer structure and semantics, which is not conveyed in a string. For example, most prompts contain both instructions ("Summarize this paper into a paragraph") and data (the paper to summarize), but these are usually not distinguished when passed to the
LLMON: An LLM-native Markup Language to Leverage Structure and Semantics at the LLM Interface
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Oncogene - Issue - nature.com science feeds
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Correction: The multifunctional RNA helicase DDX39A drives glioblastoma progression by modulating WISP1 alternative splicing that induces an immunosuppressive macrophage polarization
Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03756-2Correction: The multifunctional RNA helicase DDX39A drives glioblastoma progression by modulating WISP1 alternative splicing that induces an immunosuppressive macrophage polarization
Correction: The multifunctional RNA helicase DDX39A drives glioblastoma progression by modulating WISP1 alternative splicing that induces an immunosuppressive macrophage polarization
Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03756-2
Correction: The multifunctional RNA helicase DDX39A drives glioblastoma progression by modulating WISP1 alternative splicing that induces an immunosuppressive macrophage polarization-
Oncogene - Issue - nature.com science feeds
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STAT3-mediated transactivation of NOVA2 promotes lung adenocarcinoma metastasis by splicing SMAD4
Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03752-6STAT3-mediated transactivation of NOVA2 promotes lung adenocarcinoma metastasis by splicing SMAD4
STAT3-mediated transactivation of NOVA2 promotes lung adenocarcinoma metastasis by splicing SMAD4
Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03752-6
STAT3-mediated transactivation of NOVA2 promotes lung adenocarcinoma metastasis by splicing SMAD4-
Nature - Issue - nature.com science feeds
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Moiré engineering of Cooper-pair density modulation states
Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10325-wResearchers created a moiré superlattice in Sb2Te3/FeTe bilayers, producing spatially modulated superconducting gaps directly imaged with Josephson scanning tunnelling microscopy and spectroscopy, tunable by replacing Sb2Te3 with Bi2Te3.
Moiré engineering of Cooper-pair density modulation states
Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10325-w
Researchers created a moiré superlattice in Sb2Te3/FeTe bilayers, producing spatially modulated superconducting gaps directly imaged with Josephson scanning tunnelling microscopy and spectroscopy, tunable by replacing Sb2Te3 with Bi2Te3.-
Nature - Issue - nature.com science feeds
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Stoichiometric FeTe is a superconductor
Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10321-0Analysis of FeTe films grown using molecular-beam epitaxy and annealed under a Te flux post-growth shows that stoichiometric FeTe is inherently a superconductor, contradicting the long-held view that it is an antiferromagnetic metal.
Stoichiometric FeTe is a superconductor
Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10321-0
Analysis of FeTe films grown using molecular-beam epitaxy and annealed under a Te flux post-growth shows that stoichiometric FeTe is inherently a superconductor, contradicting the long-held view that it is an antiferromagnetic metal.-
Nature Biotechnology - Issue - nature.com science feeds
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Scalable homology detection with ERAST
Nature Biotechnology, Published online: 01 April 2026; doi:10.1038/s41587-026-03051-1ERAST speeds up homology search and provides a vector database for 1 billion biological sequences.
Scalable homology detection with ERAST
Nature Biotechnology, Published online: 01 April 2026; doi:10.1038/s41587-026-03051-1
ERAST speeds up homology search and provides a vector database for 1 billion biological sequences.-
Nature - Issue - nature.com science feeds
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General scales unlock AI evaluation with explanatory and predictive power
Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10303-2A fully automated methodology based on rubrics capturing a broad range of cognitive and intellectual demands is illustrated using LLMs and tasks, demonstrating a new way to evaluate the capabilities of AI systems and anticipate their performance.
General scales unlock AI evaluation with explanatory and predictive power
Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10303-2
A fully automated methodology based on rubrics capturing a broad range of cognitive and intellectual demands is illustrated using LLMs and tasks, demonstrating a new way to evaluate the capabilities of AI systems and anticipate their performance.-
Omics In Lung
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Catgut implantation at acupoints improves anti-PD-1 inhibitor efficacy in lung cancer by inducing immune responses and remodeling the tumor microenvironment
Cancer Immunol Immunother. 2026 Mar 31;75(4):126. doi: 10.1007/s00262-026-04368-1.ABSTRACTWhile anti-programmed death-1 (anti-PD-1) therapy has revolutionized lung cancer treatment, its efficacy remains limited by an immunosuppressive tumor microenvironment (TME). We therefore investigated whether combining anti-PD-1 inhibitor with catgut embedding at the Zusanli acupoint (CIAA) could enhance anti-tumor immunity by reprogramming the TME in a lung cancer mouse model. Combining in vivo tumor monit
Catgut implantation at acupoints improves anti-PD-1 inhibitor efficacy in lung cancer by inducing immune responses and remodeling the tumor microenvironment
Cancer Immunol Immunother. 2026 Mar 31;75(4):126. doi: 10.1007/s00262-026-04368-1.
ABSTRACT
While anti-programmed death-1 (anti-PD-1) therapy has revolutionized lung cancer treatment, its efficacy remains limited by an immunosuppressive tumor microenvironment (TME). We therefore investigated whether combining anti-PD-1 inhibitor with catgut embedding at the Zusanli acupoint (CIAA) could enhance anti-tumor immunity by reprogramming the TME in a lung cancer mouse model. Combining in vivo tumor monitoring, multi-parametric immune profiling (flow cytometry, IHC, ELISA), and multi-omics analyses (transcriptomics and metabolomics), we found that the combination therapy was associated with enhanced tumor growth inhibition. This effect correlated with a comprehensive TME transformation: conversion to an immunologically active state with increased effector immune cell infiltration (CD8⁺ T, CD4⁺ T, B cells, macrophages) and decreased regulatory T cells, coupled with suppression of pro-tumorigenic factors (VEGF, IL-6). Integrated omics analysis suggests that the combined treatment may modulate tumor-stroma interaction pathways (e.g., PI3K-Akt, focal adhesion) and rewire immunometabolic networks (e.g., tryptophan metabolism). Our study provides hypothesis-generating correlative data positioning CIAA as a potential adjunct capable of remodeling the TME to potentiate anti-PD-1 therapy in lung cancer.
PMID:41915222 | PMC:PMC13038699 | DOI:10.1007/s00262-026-04368-1