Normal view
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cs.AI, q-bio.NC updates on arXiv.org
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SAM: State-Adaptive Memory for Long-Horizon Reasoning Agent
arXiv:2605.24468v1 Announce Type: new Abstract: Long-horizon agentic reasoning requires large language models to act over long interaction histories containing thoughts, tool calls, observations, and partial conclusions. The challenge is not merely that these histories grow long, but that information needed for the current decision may be scattered across distant steps and only become relevant later. Existing approaches address this difficulty by truncating the interaction history, compressing
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cs.AI, q-bio.NC updates on arXiv.org
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AgentFugue: Agent Scaling for Long-Horizon Tasks through Collective Reasoning
arXiv:2605.24486v1 Announce Type: new Abstract: Recent progress on long-horizon agentic tasks has been driven largely by scaling up individual agents through stronger models, better tools, and more effective scaffolding. In contrast, much less is understood about scaling out: whether multiple peer agents, all targeting the same task, can become an additional source of capability without relying on explicit role specialization or workflow orchestration. We study this question and propose AgentFu
AgentFugue: Agent Scaling for Long-Horizon Tasks through Collective Reasoning
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cs.AI, q-bio.NC updates on arXiv.org
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Reasoning as an Attack Surface: Adaptive Evolutionary CoT Jailbreaks for LLMs
arXiv:2605.24497v1 Announce Type: new Abstract: Large Reasoning Models (LRMs) have demonstrated remarkable capabilities in reasoning and generation tasks and are increasingly deployed in real-world applications. However, their explicit chain-of-thought (CoT) mechanism introduces new security risks, making them particularly vulnerable to jailbreak attacks. Existing approaches often rely on static CoT templates to elicit harmful outputs, but such fixed designs suffer from limited diversity, adapt
Reasoning as an Attack Surface: Adaptive Evolutionary CoT Jailbreaks for LLMs
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cs.AI, q-bio.NC updates on arXiv.org
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DarkForest: Less Talk, Higher Accuracy for Multi-Agent LLMs
arXiv:2605.25188v1 Announce Type: new Abstract: Multi-agent LLM systems improve reasoning by combining outputs from multiple agents, but interaction-heavy methods can introduce error propagation and high communication overhead. When agents exchange raw responses or reasoning traces, incorrect intermediate reasoning may be adopted and amplified, leading to confident but wrong consensus; multi-round communication also increases token consumption, latency, and inference cost. In this paper, we pro
DarkForest: Less Talk, Higher Accuracy for Multi-Agent LLMs
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cs.AI, q-bio.NC updates on arXiv.org
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Distributionally Robust Transfer Learning with Structurally Missing Covariates, with Application to Cross-National Cardiac Arrest Prediction
arXiv:2605.24212v1 Announce Type: cross Abstract: Deploying clinical prediction models across healthcare systems often fails when key training covariates are unavailable at deployment and labeled outcomes are limited in the target domain. For example, high-performing models for out-of-hospital cardiac arrest (OHCA) rely on detailed prehospital measurements routinely collected in high-resource settings but unavailable in many international registries. Existing methods either discard missing cova
Distributionally Robust Transfer Learning with Structurally Missing Covariates, with Application to Cross-National Cardiac Arrest Prediction
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Nature Medicine
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AI-induced never-skilling in medical education
Nature Medicine, Published online: 22 May 2026; doi:10.1038/s41591-026-04438-yWill medical trainees who rely on AI fail to develop foundational independent clinical reasoning? This Perspective outlines a precautionary framework to preserve foundational competence while supporting safe and effective AI integration in medical training.
AI-induced never-skilling in medical education
Nature Medicine, Published online: 22 May 2026; doi:10.1038/s41591-026-04438-y
Will medical trainees who rely on AI fail to develop foundational independent clinical reasoning? This Perspective outlines a precautionary framework to preserve foundational competence while supporting safe and effective AI integration in medical training.-
Omics in Gastric
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Characterization of dysbiosis patterns in gut microbiota of digestive system cancers: an umbrella review
Front Microbiol. 2026 Apr 28;17:1782471. doi: 10.3389/fmicb.2026.1782471. eCollection 2026.ABSTRACTDigestive system cancers (DSCs) represent a substantial global health burden. In recent years, the role of gut microbiota in the DSCs has garnered considerable attention, but its change pattern during tumor progression and the specific mechanisms are still not fully understood. We conducted a comprehensive systematic review to characterize patterns of gut microbiota dysbiosis across different DSC t
Characterization of dysbiosis patterns in gut microbiota of digestive system cancers: an umbrella review
Front Microbiol. 2026 Apr 28;17:1782471. doi: 10.3389/fmicb.2026.1782471. eCollection 2026.
ABSTRACT
Digestive system cancers (DSCs) represent a substantial global health burden. In recent years, the role of gut microbiota in the DSCs has garnered considerable attention, but its change pattern during tumor progression and the specific mechanisms are still not fully understood. We conducted a comprehensive systematic review to characterize patterns of gut microbiota dysbiosis across different DSC types and assess their clinical significance. We systematically searched four English and three Chinese databases up to January 2025 to identify systematic reviews focused on the dynamic characteristics of the gut microbiota during gastrointestinal tumorigenesis. Microbiota biodiversity and taxonomic composition were extracted to identify specific signatures associated with DSCs. The ROBIS tool was used to evaluate the methodological quality of the included studies. Ultimately, 59 studies involving six distinct DSC types were included. Data synthesis and comparison revealed distinct microbiota profiles across DSCs. At the phylum level, Bacillota was decreased in esophageal cancer (EC) and pancreatic ductal adenocarcinoma (PDAC), Pseudomonadota was augmented in EC but exhibited divergent trajectories in colorectal cancer (CRC) and PDAC. Genus-level analyses revealed Veillonella enrichment in EC and PDAC, and Fusobacterium outgrowth in EC, gastric cancer (GC) and CRC. Parvimonas and Streptococcus showed a concordant ascending trend in GC and CRC. Prevotella was overrepresented in EC and GC. This synthesis delineates a qualitative landscape of gut microbiota imbalances associated with various DSCs, highlighting the potential for these microbial shifts to serve as markers for early detection and targeted therapy. Multiomics integration and prospective cohort studies should be prioritized to accelerate clinical translation.
PMID:42131199 | PMC:PMC13161176 | DOI:10.3389/fmicb.2026.1782471
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Oncogene - Issue - nature.com science feeds
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Granzyme B-based CAR-T cells targeting membrane-bound HSP70 suppress solid tumor growth and metastasis
Oncogene, Published online: 18 April 2026; doi:10.1038/s41388-026-03797-7Granzyme B-based CAR-T cells targeting membrane-bound HSP70 suppress solid tumor growth and metastasis
Granzyme B-based CAR-T cells targeting membrane-bound HSP70 suppress solid tumor growth and metastasis
Oncogene, Published online: 18 April 2026; doi:10.1038/s41388-026-03797-7
Granzyme B-based CAR-T cells targeting membrane-bound HSP70 suppress solid tumor growth and metastasis-
Nature - Issue - nature.com science feeds
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Autonomous closed-loop framework for reproducible perovskite solar cells
Nature, Published online: 14 April 2026; doi:10.1038/s41586-026-10482-yAutonomous closed-loop framework for reproducible perovskite solar cells
Autonomous closed-loop framework for reproducible perovskite solar cells
Nature, Published online: 14 April 2026; doi:10.1038/s41586-026-10482-y
Autonomous closed-loop framework for reproducible perovskite solar cells-
cs.AI, q-bio.NC updates on arXiv.org
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ART: Adaptive Relational Transformer for Pedestrian Trajectory Prediction with Temporal-Aware Relations
arXiv:2604.03649v1 Announce Type: cross Abstract: Accurate prediction of real-world pedestrian trajectories is crucial for a wide range of robot-related applications. Recent approaches typically adopt graph-based or transformer-based frameworks to model interactions. Despite their effectiveness, these methods either introduce unnecessary computational overhead or struggle to represent the diverse and time-varying characteristics of human interactions. In this work, we present an Adaptive Relati
ART: Adaptive Relational Transformer for Pedestrian Trajectory Prediction with Temporal-Aware Relations
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cs.AI, q-bio.NC updates on arXiv.org
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FAST-CAD: A Fairness-Aware Framework for Non-Contact Stroke Diagnosis
arXiv:2511.08887v4 Announce Type: replace-cross Abstract: Stroke is an acute cerebrovascular disease, and timely diagnosis significantly improves patient survival. However, existing automated diagnosis methods suffer from fairness issues across demographic groups, potentially exacerbating healthcare disparities. In this work we propose FAST-CAD, a theoretically grounded framework that combines domain-adversarial training (DAT) with group distributionally robust optimization (Group-DRO) for fair
FAST-CAD: A Fairness-Aware Framework for Non-Contact Stroke Diagnosis
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cs.AI, q-bio.NC updates on arXiv.org
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GPA: Learning GUI Process Automation from Demonstrations
arXiv:2604.01676v2 Announce Type: replace-cross Abstract: GUI Process Automation (GPA) is a lightweight but general vision-based Robotic Process Automation (RPA), which enables fast and stable process replay with only a single demo. Addressing the fragility of traditional RPA and the non-deterministic risks of current vision language model-based GUI agents, GPA introduces three core benefits: (1) Robustness via Sequential Monte Carlo-based localization to handle rescaling and detection uncertai
GPA: Learning GUI Process Automation from Demonstrations
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Cell Death Discovery nature.com science feeds
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FGFR1 suppresses ovarian cancer progression by modulating SIRT3-dependent lactylation and metabolic reprogramming
Cell Death Discovery, Published online: 07 April 2026; doi:10.1038/s41420-026-03054-6FGFR1 suppresses ovarian cancer progression by modulating SIRT3-dependent lactylation and metabolic reprogramming
FGFR1 suppresses ovarian cancer progression by modulating SIRT3-dependent lactylation and metabolic reprogramming
Cell Death Discovery, Published online: 07 April 2026; doi:10.1038/s41420-026-03054-6
FGFR1 suppresses ovarian cancer progression by modulating SIRT3-dependent lactylation and metabolic reprogramming-
cs.AI, q-bio.NC updates on arXiv.org
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GPA: Learning GUI Process Automation from Demonstrations
arXiv:2604.01676v1 Announce Type: cross Abstract: GUI Process Automation (GPA) is a lightweight but general vision-based Robotic Process Automation (RPA), which enables fast and stable process replay with only a single demo. Addressing the fragility of traditional RPA and the non-deterministic risks of current vision language model-based GUI agents, GPA introduces three core benefits: (1) Robustness via Sequential Monte Carlo-based localization to handle rescaling and detection uncertainty; (2)
GPA: Learning GUI Process Automation from Demonstrations
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npj Digital Medicine
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Rapid and noninvasive artificial intelligence-assisted diagnostic method for oral squamous cell carcinoma
npj Digital Medicine, Published online: 31 March 2026; doi:10.1038/s41746-026-02527-3Rapid and noninvasive artificial intelligence-assisted diagnostic method for oral squamous cell carcinoma
Rapid and noninvasive artificial intelligence-assisted diagnostic method for oral squamous cell carcinoma
npj Digital Medicine, Published online: 31 March 2026; doi:10.1038/s41746-026-02527-3
Rapid and noninvasive artificial intelligence-assisted diagnostic method for oral squamous cell carcinoma-
cs.AI, q-bio.NC updates on arXiv.org
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MCP Security Bench (MSB): Benchmarking Attacks Against Model Context Protocol in LLM Agents
arXiv:2510.15994v2 Announce Type: replace-cross Abstract: The Model Context Protocol (MCP) standardizes how large language model (LLM) agents discover, describe, and call external tools. While MCP unlocks broad interoperability, it also enlarges the attack surface by making tools first-class, composable objects with natural-language metadata, and standardized I/O. We present MSB (MCP Security Benchmark), the first end-to-end evaluation suite that systematically measures how well LLM agents resi
MCP Security Bench (MSB): Benchmarking Attacks Against Model Context Protocol in LLM Agents
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cs.AI, q-bio.NC updates on arXiv.org
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TrasMuon: Trust-Region Adaptive Scaling for Orthogonalized Momentum Optimizers
arXiv:2602.13498v2 Announce Type: replace-cross Abstract: Muon-style optimizers leverage Newton-Schulz (NS) iterations to orthogonalize updates, yielding update geometries that often outperform Adam-series methods. However, this orthogonalization discards magnitude information, rendering training sensitive to step-size hyperparameters and vulnerable to high-energy bursts. To mitigate this, we introduce TrasMuon (\textbf{T}rust \textbf{R}egion \textbf{A}daptive \textbf{S}caling \textbf{Muon}). T
TrasMuon: Trust-Region Adaptive Scaling for Orthogonalized Momentum Optimizers
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cs.AI, q-bio.NC updates on arXiv.org
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Anatomy of Agentic Memory: Taxonomy and Empirical Analysis of Evaluation and System Limitations
arXiv:2602.19320v1 Announce Type: cross Abstract: Agentic memory systems enable large language model (LLM) agents to maintain state across long interactions, supporting long-horizon reasoning and personalization beyond fixed context windows. Despite rapid architectural development, the empirical foundations of these systems remain fragile: existing benchmarks are often underscaled, evaluation metrics are misaligned with semantic utility, performance varies significantly across backbone models,
Anatomy of Agentic Memory: Taxonomy and Empirical Analysis of Evaluation and System Limitations
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cs.AI, q-bio.NC updates on arXiv.org
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Buy versus Build an LLM: A Decision Framework for Governments
arXiv:2602.13033v2 Announce Type: replace-cross Abstract: Large Language Models (LLMs) represent a new frontier of digital infrastructure that can support a wide range of public-sector applications, from general purpose citizen services to specialized and sensitive state functions. When expanding AI access, governments face a set of strategic choices over whether to buy existing services, build domestic capabilities, or adopt hybrid approaches across different domains and use cases. These are c
Buy versus Build an LLM: A Decision Framework for Governments
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cs.AI, q-bio.NC updates on arXiv.org
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TrasMuon: Trust-Region Adaptive Scaling for Orthogonalized Momentum Optimizers
arXiv:2602.13498v1 Announce Type: cross Abstract: Muon-style optimizers leverage Newton-Schulz (NS) iterations to orthogonalize updates, yielding update geometries that often outperform Adam-series methods. However, this orthogonalization discards magnitude information, rendering training sensitive to step-size hyperparameters and vulnerable to high-energy bursts. To mitigate this, we introduce TrasMuon (\textbf{T}rust \textbf{R}egion \textbf{A}daptive \textbf{S}caling \textbf{Muon}). TrasMuon