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Omni Interaction Agent Technical Report

arXiv:2609.08977v2 Announce Type: replace-cross Abstract: In this work, we present Gander, an end-to-end model that unifies omni perception, realtime interaction, and agentic capabilities within a single framework. In contrast to turn-based conventional paradigms, Gander continuously receives streaming inputs across multiple modalities, including video, speech, and text, enabling natural full-duplex interaction in both everyday conversations and complex workflow-oriented agent scenarios. Users can interrupt the model at any time, while the model can also proactively provide intermediate feedback or ask follow up questions. To natively support these capabilities, Gander adopts two key architectural designs: 1) It employs a Cerebellum-Brain collaborative framework, in which the Cerebellum is responsible for realtime interaction and omni conversational capabilities, while the Brain handles complex reasoning and higher-level agentic tasks. The two components interact continuously through tool calling and the agent orchestration runtime. 2) The Cerebellum is built upon a streaming Thinker-Talker architecture, user inputs and model outputs are further flattened into an ordered token stream at the chunk level, providing a unified representation for low latency, continuous interaction. We conduct comprehensive evaluations of Gander across four dimensions: conversational ability, omni understanding, interactive capability, and agentic intelligence. Internal human evaluations demonstrate that Gander maintains the natural and expressive spoken dialogue capabilities of SOTA open source models while achieving competitive performance in omni interaction. Gander also demonstrates robustness in challenging real-world scenarios, including background noise interference, multi-party interactions, and backchannel communication. We release Gander together with its models, code, and data to facilitate further research and development in the community.

Targeting peripheral 5-HT2AR enhances antitumor immunity in colorectal cancer

By selectively targeting peripheral 5-HT2AR without inducing psychedelic effects, a non-brain-penetrant agonist boosts antitumor CD8+ T cell immunity and improves immunotherapy responses in preclinical models of colorectal cancer.

ClawSafety: "Safe" LLMs, Unsafe Agents

arXiv:2604.01438v1 Announce Type: new Abstract: Personal AI agents like OpenClaw run with elevated privileges on users' local machines, where a single successful prompt injection can leak credentials, redirect financial transactions, or destroy files. This threat goes well beyond conventional text-level jailbreaks, yet existing safety evaluations fall short: most test models in isolated chat settings, rely on synthetic environments, and do not account for how the agent framework itself shapes safety outcomes. We introduce CLAWSAFETY, a benchmark of 120 adversarial test scenarios organized along three dimensions (harm domain, attack vector, and harmful action type) and grounded in realistic, high-privilege professional workspaces spanning software engineering, finance, healthcare, law, and DevOps. Each test case embeds adversarial content in one of three channels the agent encounters during normal work: workspace skill files, emails from trusted senders, and web pages. We evaluate five frontier LLMs as agent backbones, running 2,520 sandboxed trials across all configurations. Attack success rates (ASR) range from 40\% to 75\% across models and vary sharply by injection vector, with skill instructions (highest trust) consistently more dangerous than email or web content. Action-trace analysis reveals that the strongest model maintains hard boundaries against credential forwarding and destructive actions, while weaker models permit both. Cross-scaffold experiments on three agent frameworks further demonstrate that safety is not determined by the backbone model alone but depends on the full deployment stack, calling for safety evaluation that treats model and framework as joint variables.

AgentRAE: Remote Action Execution through Notification-based Visual Backdoors against Screenshots-based Mobile GUI Agents

arXiv:2603.23007v1 Announce Type: cross Abstract: The rapid adoption of mobile graphical user interface (GUI) agents, which autonomously control applications and operating systems (OS), exposes new system-level attack surfaces. Existing backdoors against web GUI agents and general GenAI models rely on environmental injection or deceptive pop-ups to mislead the agent operation. However, these techniques do not work on screenshots-based mobile GUI agents due to the challenges of restricted trigger design spaces, OS background interference, and conflicts in multiple trigger-action mappings. We propose AgentRAE, a novel backdoor attack capable of inducing Remote Action Execution in mobile GUI agents using visually natural triggers (e.g., benign app icons in notifications). To address the underfitting caused by natural triggers and achieve accurate multi-target action redirection, we design a novel two-stage pipeline that first enhances the agent's sensitivity to subtle iconographic differences via contrastive learning, and then associates each trigger with a specific mobile GUI agent action through a backdoor post-training. Our extensive evaluation reveals that the proposed backdoor preserves clean performance with an attack success rate of over 90% across ten mobile operations. Furthermore, it is hard to visibly detect the benign-looking triggers and circumvents eight representative state-of-the-art defenses. These results expose an overlooked backdoor vector in mobile GUI agents, underscoring the need for defenses that scrutinize notification-conditioned behaviors and internal agent representations.

Think with 3D: Geometric Imagination Grounded Spatial Reasoning from Limited Views

arXiv:2510.18632v4 Announce Type: replace-cross Abstract: Though recent advances in vision-language models (VLMs) have achieved remarkable progress across a wide range of multimodal tasks, understanding 3D spatial relationships from limited views remains a significant challenge. Previous reasoning methods typically rely on pure text (e.g., topological cognitive maps) or on 2D visual cues. However, their limited representational capacity hinders performance in specific tasks that require 3D spatial imagination. To address this limitation, we propose 3DThinker, a framework that can effectively exploits the rich geometric information embedded within images while reasoning, like humans do. Our framework is the first to enable 3D mentaling during reasoning without any 3D prior input, and it does not rely on explicitly labeled 3D data for training. Specifically, our training consists of two stages. First, we perform supervised training to align the 3D latent generated by VLM while reasoning with that of a 3D foundation model (e.g., VGGT). Then, we optimize the entire reasoning trajectory solely based on outcome signals, thereby refining the underlying 3D mentaling. Extensive experiments across multiple benchmarks show that 3DThinker consistently outperforms strong baselines and offers a new perspective toward unifying 3D representations into multimodal reasoning. Our code is available at https://github.com/zhangquanchen/3DThinker.
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