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Received — 13 April 2026 ⏭

Engineered immunosuppressive dendritic cells protect against cardiac remodelling

✇Nature - Issue - nature.com science feeds
By: Xiaoying Li · Jiamin Li · Guohua Li · Lisheng Zhu · Guo Cheng · Huanqiang Li · Hao Lin · Ningqing Jia · Xiaoqian Hong · Ye Liu · Zhiwei Zhong · Yize Chen · Biqing Wang · Jing Zhao · Zhenqi Hua · Lingjun Wang · Qiming Chen · Peijie Zheng · Shuyuan Sheng · Songting Gu · Cheng Ni · Shuchang Ye · Changle Ke · Feimu Zhang · Mo Li · Shaohui Shi · Junhua He · Yan Wu · Yinghui Xu · Minjian Kong · Qi Chen · Huajun Li · Yu Zhang · Jianzhong Sun · Guanhua Hu · Chengchen Zhao · Yiping Dong · Lili Yu · Yang Xu · Xinyang Hu
8 April 2026 at 08:00

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10346-5

Lesion-targeted immune modulation is a feasible strategy to control cardiac fibrosis, and engineered dendritic cells are a promising therapeutic platform for treating cardiac remodelling and heart failure.

PIAS4 inhibition induces cell cycle arrest and exhibits a synergistic effect in combination with CDK4/6 inhibitor in breast cancer treatment

✇Oncogene - Issue - nature.com science feeds
By: Hui Chen · Xinyang Hu · Lifeng Feng · Xiaoqing Cheng · Liyuan Zhu · Fei Xu · Tao Zhu · Yongmei Gao · Jin Wang · Hongchuan Jin · Zhinong Jiang
7 April 2026 at 08:00

Oncogene, Published online: 07 April 2026; doi:10.1038/s41388-026-03753-5

PIAS4 inhibition induces cell cycle arrest and exhibits a synergistic effect in combination with CDK4/6 inhibitor in breast cancer treatment
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