arXiv:2604.03454v1 Announce Type: cross Abstract: Rare diseases often manifest with distinctive facial phenotypes in children, offering valuable diagnostic cues for clinicians and AI-assisted screening systems. However, progress in this field is severely limited by the scarcity of curated, ethically sourced facial data and the high similarity among phenotypes across different conditions. To address these challenges, we introduce RDFace, a curated benchmark dataset comprising 456 pediatric facial images spanning 103 rare genetic conditions (average 4.4 samples per condition). Each ethically verified image is paired with standardized metadata. RDFace enables the development and evaluation of data-efficient AI models for rare disease diagnosis under real-world low-data constraints. We benchmark multiple pretrained vision backbones using cross-validation and explore synthetic augmentation with DreamBooth and FastGAN. Generated images are filtered via facial landmark similarity to maintain phenotype fidelity and merged with real data, improving diagnostic accuracy by up to 13.7% in ultra-low-data regimes. To assess semantic validity, phenotype descriptions generated by a vision-language model from real and synthetic images achieve a report similarity score of 0.84. RDFace establishes a transparent, benchmark-ready dataset for equitable rare disease AI research and presents a scalable framework for evaluating both diagnostic performance and the integrity of synthetic medical imagery.

arXiv:2603.02266v1 Announce Type: cross Abstract: Test-Time Scaling has shown notable efficacy in addressing complex problems through scaling inference compute. However, within Large Audio-Language Models (LALMs), an unintuitive phenomenon exists: post-training models for structured reasoning trajectories results in marginal or even negative gains compared to post-training for direct answering. To investigate it, we introduce CAFE, an evaluation framework designed to precisely quantify audio reasoning errors. Evaluation results reveal LALMs struggle with perception during reasoning and encounter a critical bottleneck: reasoning performance suffers from audio perception decay as reasoning length extends. To address it, we propose MPAR$^2$, a paradigm that encourages dynamic perceptual reasoning and decomposes complex questions into perception-rich sub-problems. Leveraging reinforcement learning, MPAR$^2$ improves perception performance on CAFE from 31.74% to 63.51% and effectively mitigates perception decay, concurrently enhancing reasoning capabilities to achieve a significant 74.59% accuracy on the MMAU benchmark. Further analysis demonstrates that MPAR$^2$ reinforces LALMs to attend to audio input and dynamically adapts reasoning budget to match task complexity.