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Mixture of Complementary Agents for Robust LLM Ensemble

arXiv:2605.24048v1 Announce Type: cross Abstract: Multi-AI collaboration, such as ensembling or debating large language models (LLMs), is a promising paradigm for aggregating information and boosting performance. A foundational step in these pipelines is to feed the responses of several proposer LLMs into a summarizer LLM, which synthesizes a better answer. However, choosing which proposers to include is non-trivial. Existing approaches primarily focus either on accuracy (picking the strongest models) or diversity (ensuring variety), and often overlook the interactions among proposers and with the summarizer. We reframe proposer selection as a combinatorial selection problem akin to feature selection, where the value of an LLM lies in its complementarity with others. However, directly applying standard feature-selection algorithms is impractical in the LLM setting due to prohibitive time complexity. Motivated by this limitation, we explore an extensive range of computationally feasible, greedy-style selection algorithms that assess complementarity using a small labeled set. Our experiments validate complementarity as a guiding principle for proposer selection and identify methods that achieve the best performance-cost trade-offs in practice.
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Evaluating AI in leukocyte classification: performance of the AI system against 15 morphology experts

npj Digital Medicine, Published online: 11 April 2026; doi:10.1038/s41746-026-02601-w

Evaluating AI in leukocyte classification: performance of the AI system against 15 morphology experts
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MARS: toward more efficient multi-agent collaboration for LLM reasoning

arXiv:2509.20502v2 Announce Type: replace-cross Abstract: Large language models (LLMs) have achieved impressive results in natural language understanding, yet their reasoning capabilities remain limited when operating as single agents. Multi-Agent Debate (MAD) has been proposed to address this limitation by enabling collaborative reasoning among multiple models in a round-table debate manner. While effective, MAD introduces substantial computational overhead due to the number of agents involved and the frequent communication required. In this paper, we propose MARS (Multi-Agent Review System), a role-based collaboration framework inspired by the review process. In MARS, an author agent generates an initial solution, reviewer agents provide decisions and comments independently, and a meta-reviewer integrates the feedback to make the final decision and guide further revision. This design enhances reasoning quality while avoiding costly reviewer-to-reviewer interactions, thereby controlling token consumption and inference time. We compared MARS with both MAD and other state-of-the-art reasoning strategies across multiple benchmarks. Extensive experiments with different LLMs show that MARS matches the accuracy of MAD while reducing both token usage and inference time by approximately 50\%. Code is available at https://github.com/xwang97/MARS.
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Epigenetic memory of colitis promotes tumour growth

Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10258-4

Colonic stem cells retain a memory of inflammation following disease resolution and there is a mechanistic link between chronic inflammation and malignancy, suggesting potential strategies to mitigate cancer risk in patients with chronic inflammatory conditions.
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HAMLET: A Hierarchical and Adaptive Multi-Agent Framework for Live Embodied Theatrics

arXiv:2507.15518v4 Announce Type: replace Abstract: Creating an immersive and interactive theatrical experience is a long-term goal in the field of interactive narrative. The emergence of large language models (LLMs) provides a new path to achieve this goal. However, existing LLM-based drama generation methods often produce models that lack initiative and cannot interact with the physical scene, while typically requiring detailed user input that diminishes the immersion of live performance. To address these challenges, we propose HAMLET, a hierarchical adaptive multi-agent framework focused on drama creation and real-time online performance. Given a simple topic, the framework first generates a narrative blueprint to guide the subsequent improvisational performance. In the online performance phase, each actor is equipped with an adaptive reasoning module that enables decision-making based on their personas, memories, goals, and emotional states during complex group chat scenarios. Beyond dialogue, actor agents engage in embodied interactions by changing the state of scene props through actions such as opening a letter or picking up a weapon, which are broadcast to update the global environmental context. To objectively assess the quality of live embodied theatrics, we establish a comprehensive evaluation method and introduce HAMLETJudge, a specialized critic model for automated evaluation. Experimental results demonstrate that HAMLET excels in creating expressive, coherent, and physically interactive theatrical experiences in an autonomous manner.
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VoiceBridge: General Speech Restoration with One-step Latent Bridge Models

arXiv:2509.25275v3 Announce Type: replace-cross Abstract: Bridge models have been investigated in speech enhancement but are mostly single-task, with constrained general speech restoration (GSR) capability. In this work, we propose VoiceBridge, a one-step latent bridge model (LBM) for GSR, capable of efficiently reconstructing 48 kHz fullband speech from diverse distortions. To inherit the advantages of data-domain bridge models, we design an energy-preserving variational autoencoder, enhancing the waveform-latent space alignment over varying energy levels. By compressing waveform into continuous latent representations, VoiceBridge models~\textit{various} GSR tasks with a~\textit{single} latent-to-latent generative process backed by a scalable transformer. To alleviate the challenge of reconstructing the high-quality target from distinctively different low-quality priors, we propose a joint neural prior for GSR, uniformly reducing the burden of the LBM in diverse tasks. Building upon these designs, we further investigate bridge training objective by jointly tuning LBM, decoder and discriminator together, transforming the model from a denoiser to generator and enabling \textit{one-step GSR without distillation}. Extensive validation across in-domain (\textit{e.g.}, denoising and super-resolution) and out-of-domain tasks (\textit{e.g.}, refining synthesized speech) and datasets demonstrates the superior performance of VoiceBridge. Demos: https://VoiceBridgedemo.github.io/.
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