(MedPage Today) -- The FDA approved apitegromab (Isembyld) injection to treat spinal muscular atrophy (SMA) in adults and pediatric patients ages 2 years and older who currently are receiving an SMN2-targeted treatment, the agency announced Friday...

(MedPage Today) -- Brain MRI surveillance without prophylactic cranial irradiation (PCI) led to improved cognitive failure-free survival (CFFS) in patients with small cell lung cancer (SCLC), the phase III MAVERICK trial showed. Patients randomized...

(MedPage Today) -- Blockbuster GLP-1 receptor agonists revolutionized obesity management in recent years, driving weight loss of up to 20%. This weight loss, however, can carry a notable downside: Studies estimate that 15% to 40% of GLP-1-induced...

(MedPage Today) -- The Trump administration's announcement that it will send $500 "rebate" checks to roughly 1 million Affordable Care Act (ACA) enrollees in 30 states ($500 million total) fits a familiar pattern: seeking political advantage through...

(MedPage Today) -- Use of adjunctive azithromycin increased among women undergoing unscheduled cesarean deliveries and postpartum infection rates fell after a landmark trial showed the antibiotic's benefits in this setting, according to a difference...

(MedPage Today) -- When a child presented to the emergency department with a brown, lace-like rash on his abdomen, it took a few weeks before physicians pinpointed the likely source. Initially, they thought it might be bruising from some kind...

(MedPage Today) -- Patients with newly diagnosed idiopathic inflammatory myopathies (IIMs) such as dermatomyositis improved more when they received intravenous immunoglobulin (IVIG) alongside prednisone than with the steroid alone in a placebo...

(MedPage Today) -- A Pennsylvania woman has died from complications associated with measles, the third death in the state this year involving the virus. The 40-year-old woman died Saturday, Jefferson County Coroner Greg Furlong said in a Facebook...

(MedPage Today) -- Note that some links may require registration or subscription. A licensed practical nurse in Pennsylvania allegedly performed an exorcism in 2025 on a nursing home resident she claimed had "demons" in her, according to a grand...

(MedPage Today) -- Survival in metastatic non-small cell lung cancer (NSCLC) did not improve with the addition of the antibody-drug conjugate (ADC) sacituzumab govitecan (Trodelvy) to immunotherapy, a large randomized trial showed. Median progression...

(MedPage Today) -- Two investigational anti-B7-H3 antibody-drug conjugates (ADCs) significantly improved survival outcomes in patients with relapsed small-cell lung cancer (SCLC), according to a pair of Chinese trials. In the TAISHAN-302 study...

(MedPage Today) -- "The underlying case is a real-but-vanilla commercial dispute." -- Christopher Robertson, JD, PhD, of Boston University, discussing a medical software company's lawsuit against a former collaborator, who helped launch a rival...

(MedPage Today) -- The CDC was founded 80 years ago with a single mission: to eradicate malaria from the U.S. By 1946, the year of the CDC's inception, malaria had devastated the nation, causing significant morbidity and mortality for more than...

(MedPage Today) -- Local consolidative therapy (LCT) after induction treatment with nivolumab (Opdivo) plus ipilimumab (Yervoy) failed to improve survival outcomes in patients with metastatic non-small cell lung cancer (NSCLC), including those...

(MedPage Today) -- Healthy Moms, Healthy Babies America, a bipartisan campaign founded by philanthropists Olivia and Tom Walton, announced a $100 million pledge to make giving birth in the U.S. safer. The 5-year commitment aims to cut the maternal...

(MedPage Today) -- A broad population of people with chronic obstructive pulmonary disease (COPD), current and former smokers alike, experienced fewer exacerbations taking a first-in-class biologic targeting interleukin (IL)-33, a pair of double...

(MedPage Today) -- Exposure to Helicobacter pylori, known for its role in gastric cancer, may also play a role in colorectal cancer (CRC), according to results from a risk-attribution modeling study. Based on estimates from 43 studies, H. pylori...

(MedPage Today) -- A panel of federal judges heard arguments Wednesday over whether prescribing rules should be tightened for mifepristone, a key drug used in the most common abortion method in the U.S., one of several ongoing efforts to restrict...

(MedPage Today) -- Autoimmune reactions to immune checkpoint inhibitors (ICIs) in cancer patients referred to rheumatologists were generally more severe than previously reported, German researchers found, with corticosteroids usually insufficient...

(MedPage Today) -- Connecticut psychiatrist Douglas Zelisko, MD, is under investigation for 21 alleged medical violations, including improper prescribing, misrepresenting a romantic partner as a licensed therapist, and engaging in inappropriate...